Correlation of stem cell count to the survival of micro fat grafts in augmenting the enophthalmic socket volume: A CT volumetry guided study /
مقارنة بين إرتباط عدد الخلايا الجزعية ببقاء الرقع الدهنيه المجهرية في زيادة حجم الحجاج الذى يعانى من العين الضامره بإستخدام الأشعة المقطعية لحساب الحجم
Aliaa Ahmed Farag Ahmed Farag Ahmed ; Supervised Tamer Ismail Gawdat , Rania Ahmed Abdel Salam , Laila Ahmed Rashed
- Cairo : charts,facsmilies , 2020
- 129 P . : Aliaa Ahmed Farag Ahmed Farag Ahmed ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Ophthalmology
Background: The use of autologous fat grafting is limited by its unpredictable survival rate. In our study we aim at studying the effect of stem cell viability, harvested from the abdomen and thigh, on autologous fat grafts survival in the orbital for treating the enophthalmic anophthalmic socket using CT volumetry. Methods: A randomized prospective interventional study including 24 patients suffering from unilateral enophthalmic anophthalmic socket. Pre-operative clinical assessment included photographs, exophthalmometry reading as well as CT volumetry for volume deficit calculations. The harvesting site was randomly allocated between patients (abdomen or thigh). Fat was sent to the laboratory to assess stem cell viabilityPatients were followed up to 6 months post-operatively. Percentage of fat retained 1 and 2 (Percentage of fat remaining at the last follow up compared to pre-operative measurements of the enophthalmic socket with the globe and without the globe respectively) was calculated as well as exophthalmometry change. Results: Mean percentage of retained fat 1 and 2 were 14.75% & 25.31% respectively. No statistically significant correlation was found between the sex, age of the patients, donor site, percentage of fat retained 1 and 2 or exophthalmometer change and the percentage of stem cell viability. Difficulty of extraction and degree of atrophia correlated significantly with percentage of fat retained 2 and not 1. Exophthalmometer change correlated significantly with percentage of fat retained 1 and not 2