02167cam a2200265 a 4500003000900000005001700009008004100026040002800067041000800095100002800103245015900131246010200290260004700392300003100439502009800470520105400568530002201622653002701644653003601671653004301707700004201750700003801792700003801830856003301868EG-GiCUC20250223032803.0210816s2021    ua d   f m    000 0 eng d  aEG-GiCUCbengcEG-GiCUC0 aeng0 aHeidi Ramadan Abdelhadi10aAnalysis of some drugs containing hydroxyl group / cHeidi Ramadan Abdelhadi ; Supervised Hala Elsayd Zaazaa , Maya Shaaban Eissa , Basma Mohamed Eltanany15aتحليل بعض الادوية التى تحتوى على مجموعة  الهيدروكسيل   aCairo : bHeidi Ramadan Abdelhadi , c2021  a181 P. : bcharts ; c25cm  aThesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Analytical Chemistry   aThis work is concerned on the quantitative determination of different drugs containing hydroxyl group, namely, Pyridoxine Hydrochloride, (PYR), Doxylamine Succinate (DOX), Chloramphenicol (CHL), Dexmethasone Sodium Phosphate (DSP) and Tetrahydrozoline Hydrochloride (THZ) in their pure form, laboratory prepared mixtures and their pharmaceutical dosage forms. In this study, different analytical techniques were developed, which include spectrophotometric, chemmometric, green chromatographic and voltammetric methods for estimation of the drugs under study and different applications were developed e.g dissolution test and bioanalytical applications. Several experimental conditions were developed for optimization of the adopted methods. Since degradation of pharmaceutical compounds may result in partial or complete loss of the pharmacological activity with propability of producing toxic or harmful substance, stability indicating assay methods were developed for the determination of the intact drug in presence of their degradation products   aIssued also as CD 4aChloramphenicol (CHL)  4aPyridoxine Hydrochloride (PYR)  4aTetrahydrozoline Hydrochloride (THZ)  0 aBasma Mohamed Eltanany , eSupervisor0 aHala Elsayd Zaazaa , eSupervisor0 aMaya Shaaban Eissa , eSupervisor  uhttp://172.23.153.220/th.pdf