02375cam a2200349 a 4500 EG-GiCUC 20250223032803.0 210816s2021 ua d f m 000 0 eng d EG-GiCUC eng EG-GiCUC eng Deposite M.Sc Cai01.08.03.M.Sc.2021.He.A Heidi Ramadan Abdelhadi Analysis of some drugs containing hydroxyl group / Heidi Ramadan Abdelhadi ; Supervised Hala Elsayd Zaazaa , Maya Shaaban Eissa , Basma Mohamed Eltanany تحليل بعض الادوية التى تحتوى على مجموعة الهيدروكسيل Cairo : Heidi Ramadan Abdelhadi , 2021 181 P. : charts ; 25cm Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Analytical Chemistry This work is concerned on the quantitative determination of different drugs containing hydroxyl group, namely, Pyridoxine Hydrochloride, (PYR), Doxylamine Succinate (DOX), Chloramphenicol (CHL), Dexmethasone Sodium Phosphate (DSP) and Tetrahydrozoline Hydrochloride (THZ) in their pure form, laboratory prepared mixtures and their pharmaceutical dosage forms. In this study, different analytical techniques were developed, which include spectrophotometric, chemmometric, green chromatographic and voltammetric methods for estimation of the drugs under study and different applications were developed e.g dissolution test and bioanalytical applications. Several experimental conditions were developed for optimization of the adopted methods. Since degradation of pharmaceutical compounds may result in partial or complete loss of the pharmacological activity with propability of producing toxic or harmful substance, stability indicating assay methods were developed for the determination of the intact drug in presence of their degradation products Issued also as CD Chloramphenicol (CHL) Pyridoxine Hydrochloride (PYR) Tetrahydrozoline Hydrochloride (THZ) Basma Mohamed Eltanany , Supervisor Hala Elsayd Zaazaa , Supervisor Maya Shaaban Eissa , Supervisor http://172.23.153.220/th.pdf Nazla Revisor Shimaa Cataloger ddc TH 81758 81758 ddc 0 CUCL cl210 2024-02-11 Cai01.08.03.M.Sc.2021.He.A 01010110083935000 2023-09-22 00:00:00 TH ddc 0 CUCL cl2u8 2024-02-11 Cai01.08.03.M.Sc.2021.He.A 01020110083935000 2023-09-22 00:00:00 83935.CD CD