Heidi Ramadan Abdelhadi creator Basma Mohamed Eltanany Supervisor Hala Elsayd Zaazaa Supervisor Maya Shaaban Eissa Supervisor text theses ua Cairo Heidi Ramadan Abdelhadi 2021 monographic eng

print

181 P. : charts ; 25cm This work is concerned on the quantitative determination of different drugs containing hydroxyl group, namely, Pyridoxine Hydrochloride, (PYR), Doxylamine Succinate (DOX), Chloramphenicol (CHL), Dexmethasone Sodium Phosphate (DSP) and Tetrahydrozoline Hydrochloride (THZ) in their pure form, laboratory prepared mixtures and their pharmaceutical dosage forms. In this study, different analytical techniques were developed, which include spectrophotometric, chemmometric, green chromatographic and voltammetric methods for estimation of the drugs under study and different applications were developed e.g dissolution test and bioanalytical applications. Several experimental conditions were developed for optimization of the adopted methods. Since degradation of pharmaceutical compounds may result in partial or complete loss of the pharmacological activity with propability of producing toxic or harmful substance, stability indicating assay methods were developed for the determination of the intact drug in presence of their degradation products specialized Heidi Ramadan Abdelhadi ; Supervised Hala Elsayd Zaazaa , Maya Shaaban Eissa , Basma Mohamed Eltanany Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Analytical Chemistry Issued also as CD Chloramphenicol (CHL) Pyridoxine Hydrochloride (PYR) Tetrahydrozoline Hydrochloride (THZ) http://172.23.153.220/th.pdf http://172.23.153.220/th.pdf EG-GiCUC 210816 20250223032803.0 eng