Value of diffusion mri versus PET CT scan in n staging of high risk primary or recurrent differentiated thyroid cancer /
دور التصوير ذو الثقل بالانتشار بواسطة الرنين المغناطيسى مقارنة بالتصوير المقطعي بالإصدار البوزترونى فى تقييم التدريج للغدد الليمفاوية المصابة بأورام خبيثة مصنفة نتيجة اورام عالية الخطورة بالغدة الدرقية او إعادة ظهورها بعد ازالتها
Ahmed Magdy Ahmed Shalash ; Supervised Ayman Abdelwahab Amin , Ayda Aly Youssef , Mai Amr Abdelwahab
- Cairo : Ahmed Magdy Ahmed Shalash , 2021
- 173 P. : charts , facsimiles ; 25cm
Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Oncology (Rdiation , Radiotherapy)
The purpose of this study was to compare diagnostic performance of the MRI with diffusion weighted images (DW-MRI) & the Positron Emission Tomography (PET-CT) in N staging of initially high risk or recurrent differentiated thyroid cancer.The study was conducted on 30 patients, each had performed both MRI with diffusion & PET-CT just before the surgical operation.The gold standard was the pathological evaluation of the surgical specimens in order to assess the sensitivity & specificity for each modality to diagnose the nodal metastasis & recurrence of the differentiated thyroid cancer. A statistical comparison of the results was made. FDG PET/ CT study was found to be a promising diagnostic modality for assessment of DTC patients, whom are at risk or with suspected recurrent regional nodal metastases.Although the reasonable specificity that is outperformed by the PET/CT over the MRI with diffusion, the sensitivity of both modalities was found to be nearly similar.By combination of both FDG PET/CT and MRI with diffusion techniques, a prominent synergistic effect was found for detection of nodal metastases in differentiated thyroid cancer and associated with superior sensitivity than using a single modality.These results will lead to open the door wide to assess the role of the PET/MRI in detection of nodal metastases in differentiated thyroid cancer