02775cam a2200349 a 4500 EG-GiCUC 20250223032904.0 211226s2021 ua dh f m 000 0 eng d EG-GiCUC eng EG-GiCUC eng Deposite M.Sc Cai01.08.03.M.Sc.2021.Ra.A Rana Elsayed Yusef Sherif Analysis of some UV filters used in skin care and cosmetic products / Rana Elsayed Yusef Sherif ; Supervised Sawsan Mohammed Amer , Ghada Abdelhamid Sedik , Hanan Mohamed Elwy تحليل لبعض مرشحات الاشعة فوق البنفسجية المستخدمة فى مستحضرات العناية بالبشرة ومستحضرات التجميل Cairo : Rana Elsayed Yusef Sherif , 2021 226 P. : charts , facsimiles ; 25cm Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Analytical Chemistry UV filters recently gained a lot of interest as they are intended to protect human skin against UV radiation, and for this reason they are increasingly added to many personal care products. This thesis deals with the study of different UV filters namely Benzophenone-4 (BZ4) and Benzophenone-3 (BZ3) in combination with Octyl methoxycinnamate (OMC) as a coformulated drug. Different analytical techniques including chromatographic, spectroscopic and electrochemical ones were adopted for the determination of the studied drugs either in their pure form or their pharmaceutical formulations. Different experimental conditions were studied till reaching the optimum conditions.The chromatographic methods utilize the power of HPLC and TLC densitometry for quantification of the studied drugs in their pure form and in presence of their stress induced degradation products.While different spectroscopic methods were introduced for BZ4 determination with acceptable results. Finally two electrochemical methods were developed and validated implying novel modified MWCNTs sensor in addition to molecularly imprinted polymer modified Carbon paste sensor for highly sensitive determination of BZ4. All suggested methods were validated according to ICH guide lines and compared statistically to reported methods where no significant difference regarding accuracy and precision was observed Issued also as CD Chromatography Spectroscopy UV filters Ghada Abdelhamid Sedik , Supervisor Hanan Mohamed Elwy , Supervisor Sawsan Mohammed Amer , Supervisor http://172.23.153.220/th.pdf Nazla Revisor Shimaa Cataloger ddc TH 83709 83709 ddc 0 CUCL cl210 2024-02-11 Cai01.08.03.M.Sc.2021.Ra.A 01010110085074000 2023-09-22 00:00:00 TH ddc 0 CUCL cl2u8 2024-02-11 Cai01.08.03.M.Sc.2021.Ra.A 01020110085074000 2023-09-22 00:00:00 85074.CD CD