03349nam a2200361 a 4500 EG-GiCUC 20250223032936.0 220817s2022 ua dh f m 000 0 eng d EG-GiCUC eng EG-GiCUC eng Deposite Ph.D Cai01.21.04.Ph.D.2022.En.E Enas Said Mohamed Abdalla Eltouny Effect Of Ultrasound On Subserosal And Intramural Fibroids: In Vitro / Enas Said Mohamed Abdalla Eltouny ; Supervised Amel Mohamed Yousef , Abeer Mohamed Eldeeb , Hosameldin Hussin kamal خارج الجسم : تأثير الموجات فوق الصوتية علي الاورام الليفية تحت المصلية و الجماعية Cairo : Enas Said Mohamed Abdalla Eltouny , 2022 119 P . : charts , facsimies ; 25cm Thesis (Ph.D.) - Cairo University - Faculty of Physical Therapy - Department of Physical Therapy for Gyneycology & obstetrics Uterine fibroids are the most common benign tumors that worsen women's health during their reproductive age. However, its negative impact on the women's quality of life, there are few conservative therapeutic options to control it. This study was conducted to investigate the effect of ultrasound waves subserosal and intramural. 46 leiomyomas were divided into 30 leiomyomas as experimental group and 16 leiomyomas as a control groups, each group was subdivided into another 3 groups (A1), (B2), and (C3), received ultrasound (continuous,1 MHZ, 2Watt/cm2) for 15, 30, and 45 minutes respectively in experimental group, while they were not exposed to ultrasound in control group. All sizes of leiomyomas were measured using the fluid displacement method before and after 15, 30, 45 minutes in both groups. The sizes of uterine leiomyomas showed a significant decrease (P-value=0.0001) in all groups (A), (B) & (C) of experimental group after the application of ultrasound, also it showed a significant decrease (P-value=0.049), (P-value=0.034) (Pvalue= 0.011) in group (A), (B) & (C) of experimental group respectively after the application of ultrasound when it compared with control group beyond 15, 30, 45 minutes after the leiomyomas excision. While, the sizes of leiomyomas showed a non-significant difference in-between groups (A), (B) & (C) after the application of ultrasound in experimental group (P=0.99) and beyond 15, 30, 45 minutes after the excision in control group (P=1.00). Histopathological evaluation depending on hematoxylin and eosin (H&E) stains and (Caspase-3) stain were performed after ultrasound application for experimental group and for only 6 leiomyomas selected randomly from control group. In hematoxylin and eosin (H&E) stains after the application of ultrasound, apoptosis was observed in 100% of leiomyoma samples in group (A), (B), and (C) Issued also as CD Ultrasound clinics histopathological evaluation Intramural Subserosal Abeer Mohamed Eldeeb , Supervisor Amel Mohamed Yousef , Supervisor Hosameldin Hussin kamal , Supervisor http://172.23.153.220/th.pdf Amira Cataloger Enas Revisor ddc TH 84748 84748 ddc 0 CUCL cl210 2024-02-11 Cai01.21.04.Ph.D.2022.En.E 01010110085678000 2023-09-22 00:00:00 TH ddc 0 CUCL cl2u8 2024-02-11 Cai01.21.04.Ph.D.2022.En.E 01020110085678000 2023-09-22 00:00:00 85678.CD CD