Taghred Rafat ElMaghawry ElRasheedy creator Mohamed Aly ElDesouky Supervisor Mohamed Osman Ibrahim Refaie Supervisor Safaa Moustafa Elkaraksy Supervisor ua Cairo Taghred Rafat ElMaghawry ElRasheedy 2006 eng Eng 174 P : charts ; 30cm Von Willebrand (vW) Protein is a large , adhesive glycoprotein of complex multimeric structure that mediates the adhesion of platelet to subendothelium after injury , thrombus Formation and coagulation , the latter as carrier for Factor VIIIit is synthesized by endothelial cells and Megakaryocytes as a primary translation product of 2813 amino acids , which are likely to be the source of vW protein in plasma and subendothelium and stored in the Weibel - Palade bodies and in an internal structure in the alpha - granule of plateletsvW protein is first synthesized as a 260 - KD precursor sub unitvWF is located on the short arm of chromosome 12 Taghred Rafat ElMaghawry ElRasheedy ; Supervised Mohammed Osman Ibrahim Refaie , Safaa Moustafa ELkarksy , Mohammed Ali El Desouky Thesis (M.Sc.) - Cairo University - Faculty Of Science - Department Of Biochemistry Issued also as CD DDAVP - - - dEAMINO - D - Arginine vasopressine von willebrand diseases von willebrand Factor http://172.23.153.220/th.pdf http://172.23.153.220/th.pdf EG-GICUC 060917 20250223032951.0 eng