TY - GEN AU - Taghred Rafat ElMaghawry ElRasheedy AU - Mohamed Aly ElDesouky , AU - Mohamed Osman Ibrahim Refaie , AU - Safaa Moustafa Elkaraksy , TI - Biochemical studies of von willebrand factor in diabetic and hypercholesterolaemic patients / PY - 2006/// CY - Cairo : PB - Taghred Rafat ElMaghawry ElRasheedy , KW - DDAVP - - - dEAMINO - D - Arginine vasopressine KW - von willebrand diseases KW - von willebrand Factor N1 - Thesis (M.Sc.) - Cairo University - Faculty Of Science - Department Of Biochemistry; Issued also as CD N2 - Von Willebrand (vW) Protein is a large , adhesive glycoprotein of complex multimeric structure that mediates the adhesion of platelet to subendothelium after injury , thrombus Formation and coagulation , the latter as carrier for Factor VIIIit is synthesized by endothelial cells and Megakaryocytes as a primary translation product of 2813 amino acids , which are likely to be the source of vW protein in plasma and subendothelium and stored in the Weibel - Palade bodies and in an internal structure in the alpha - granule of plateletsvW protein is first synthesized as a 260 - KD precursor sub unitvWF is located on the short arm of chromosome 12 UR - http://172.23.153.220/th.pdf ER -