Synthesis of novel heterocyclic compounds and their biological evaluation as phosphodiesterase inhibitors and anticancer agents / Heba Abdulla Mohamed ; Supervised Ashraf H. Abadi
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TextLanguage: English Publication details: Cairo : Heba Abdulla Mohamed , 2010Description: 139 Leaves : charts ; 30cmOther title: - تشييد مركبات جديدة غير متجانسة الحلقة و دراسة تأثيراتها الحيوية كمثبطات للإنزيم فوسفودايستريز و كعقاقير مضادة للسرطان [Added title page title]
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Thesis
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قاعة الثقاقات الاجنبية - الدور الثالث | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.34.M.Sc.2010.He.S (Browse shelf(Opens below)) | Not for loan | 01010110060207000 |
Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry
Tadalafil is an orally administered drug used to treat male erectile dysfunction (impotence). It is a Ý-carboline derivative that inhibits PDE 5, leading to elevation of cGMP, vascular relaxation in the corpora cavernosa and penile erection during sexual stimulation. Recently, studies have shown that phosphodiesterases including PDE5 are overexpressed in malignant tumors
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