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Regeneration potential of bone marrow derived mesenchymal stem cells and platelet rich plasma (prp) on irradiation-induced damage of submandibular salivary gland in albino rats/ by Nermine Hani Mohamed ; Supervised Prof.Dr Sahar Shawkat, Prof.Dr. Marwa Samir Moussa, Prof.Dr.Nermeen El-moataz Bella.

By: Contributor(s): Material type: TextLanguage: English Summary language: English, Arabic Producer: 2021Description: 149 P.: Facsmiles , charts , photographs ; 25 cm CDContent type:
  • text
Media type:
  • Unmediated
Carrier type:
  • volume
Other title:
  • تأثير الخلايا الجذعية المستمدة من نخاع العظام والبلازما الغنية بالصفيحات على إعادة تجديد الغدد اللعابية المتضرره من الاشعاع في الفئران البيضاء [Added title page title]
Subject(s): DDC classification:
  • 610
Available additional physical forms:
  • Issued also as CD
Dissertation note: Thesis (M.Sc. ) - Cairo University - Faculty of Dentistry - Department of Oral Biology Summary: Aim Compare between the effects of PRP, bone marrow mononuclear cells (BMMCs) and their combination on regeneration of irradiated rat submandibular salivary glands (SMD). Methodology: 32 healthy male albino rats were irradiated with a single dose of 6 Gy then classified into four main groups of 8 rats. The rats of group A received no treatment after irradiation. Group B rats received single intraglandular injection of BMMCs (0.5{u00D7}105) cells/100oL, 24 hours (hr) after irradiation. Group C rats, received a single intraglandular injection of 100 ol of PRP 24 hr after irradiation. In group D, 24 hr after irradiation, the rats received single intraglandular injection of (0.5{u00D7}105) BMMCs suspended in 100 ol PRP supernatant. Histopathological examination of all groups was performed at 1- and 2-weeks post irradiation. The histological changes were evaluated histomorphometrically in term of total surface area percentage of acini. TGF- Ý1 expression was measured using Polymerase chain reaction (PCR).
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Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.09.12.M.Sc.2021.Ne.R. (Browse shelf(Opens below)) Not for loan 01010110085599000
CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai09.12.M.Sc.2021.Ne.R. (Browse shelf(Opens below)) 85599 CD Not for loan 01020110085599000

Thesis (M.Sc. ) - Cairo University - Faculty of Dentistry - Department of Oral Biology

Bibliography: p. 150-167.

Aim Compare between the effects of PRP, bone marrow mononuclear cells (BMMCs) and their combination on regeneration of irradiated rat submandibular salivary glands (SMD). Methodology: 32 healthy male albino rats were irradiated with a single dose of 6 Gy then classified into four main groups of 8 rats. The rats of group A received no treatment after irradiation. Group B rats received single intraglandular injection of BMMCs (0.5{u00D7}105) cells/100oL, 24 hours (hr) after irradiation. Group C rats, received a single intraglandular injection of 100 ol of PRP 24 hr after irradiation. In group D, 24 hr after irradiation, the rats received single intraglandular injection of (0.5{u00D7}105) BMMCs suspended in 100 ol PRP supernatant. Histopathological examination of all groups was performed at 1- and 2-weeks post irradiation. The histological changes were evaluated histomorphometrically in term of total surface area percentage of acini. TGF- Ý1 expression was measured using Polymerase chain reaction (PCR).

Issued also as CD

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