000			05176namaa22004331i 4500
003			OSt
005			20250223033407.0
008			250109s2023 |||a|||f m||| 000 0 eng d
040			_aEG-GICUC _beng _cEG-GICUC _dEG-GICUC _erda
041	0		_aeng _beng _bara
049			_aDeposit
082	0	4	_a616.24
092			_a616.24 _221
097			_aPh.D
099			_aCai01.11.06.Ph.D.2023.As.L
100	0		_aAfnan Nabil Fatehi Abdelghaffar, _epreparation.
245	1	0	_aLung sequale of pneumonic covid / _cBy Afnan Nabil Fatehi Abdelghaffar; supervisors Prof. Yosri Mohamed Kamel Akl, Prof. Dr. Youssef Amin Soliman, Prof. Dr. Sabah Ahmed Mohamed.
246	1	5	_aتوابع ما بعد الإصابة بعدوى فيروس كورونا على الرئة /
264		0	_c2023.
300			_a129 pages : _billustrations ; _c25 cm. + _eCD.
336			_atext _2rda content
337			_aUnmediated _2rdamedia
338			_avolume _2rdacarrier
502			_aThesis (Ph.D)-Cairo University, 2023.
504			_aBibliography: pages 114-129.
520			_aAim: The aim of this study is to assess the clinical and radiological lung abnormalities and sequle of COVID 19 infection and to formulate a speculation about the possible treatment regimen according to different outcomes. Patients and methods: •Through History taking: dyspnea using MMRC and its progression, cough, anosmia, palpitation, easy fatigability. •Labs is withdrawen ( CBC ,CRP, D-dimer,ferritin) •Computed tomography of the chest, determination of the most prominent pattern in CT whether OP or fibrotic. •CT pulmonary angiography when indicated. •Re-evaluation of CT chest after one, three and six months. •Stair climbing test as a marker of exercise tolerance with assessment of desaturation difference between the baseline SPO2 and post exercise SPO2. •Data will be tabulated and statistically analyzed. Results: highly statistical significant increased Lymphocytes at 3 months was detected when compared with lymphocytes at admission. No statistical significant correlation between CT score at admission and number of co-morbidities. Increased So2 associated with low CT score, while increase CRP level associated with deterioration of CT lung score. Decrease lymphocytes associated with high CT score, on the other han, high level of ferritin associated with icreased CT score. It was found that most of the lung abnormalities were reticulations and diffuse ground-glass opacities. There was a strong relationship between high C-reactive protein and D-dimer and the severity of Covid infection. There was a highly statistical significant relationship between high C-reactive protein and D-dimer and the severity of Covid infection. No statistically significant differences were observed between the patients under study in terms of the relationship of smoking with the severity of lung injury. It has also been shown that the severity of CT score gradually decreases over time, regardless of the treatment that was given(Pirfinidone or colchicine) , or the degree of severity of COVID disease itself.
520			_a الهدف من الدراسة: تم اجراء هذه الدراسة بهدف تقييم توابع ما بعد الإصابة بعدوى فيروس كورونا على الرئة وصياغة تصور حول نظم العلاج الممكن وفقا للنتائج المختلفة. المرضى وطرق البحث: شملت هذه الدراسة 100 مريض مصاب بالالتهاب الرئوي الناجم عن فيروس كورونا والذين تم تقديمهم إلى وحدة عزل الصدر بمستشفيات جامعة القاهرة في الفترة من أغسطس 2020 إلى مارس 2022. النتائج: تبين أن معظم اصابات الرئة كانت من النوع مثل خطوط شبكية وعتامات زجاجية أرضية منتشرة. وقد كانت هناك علاقة قوية بين ارتفاع بروتين سي التفاعلي و دي دايمر وشدة الاصابة بفيروس كوفيد. لم يلاحظ أي فروق ذات دلالة إحصائية بين المرضى قيد الدراسة من حيث علاقة التدخين مع شدة اصابة الرئة. كما تبين أن شدة تأثر الأشعة المقطعية تقل تدريجيا مع مرور الوقت بغض النظر عن العلاج الذي تم اعطاؤه أو عن شدة تأثر الرئة بالمرض أو درجة شدة المرض نفسه.
530			_aIssues also as CD.
546			_aText in English and abstract in English.
650		7	_aDiseases of the lungs _2qrmak
653		0	_alung abnormalities _apost COVID _aGGO _aCT score _aantifibrotic drugs
700	0		_aYosri Mohamed Kamel Akl _ethesis advisor.
700	0		_aYoussef Amin Soliman _ethesis advisor.
700	0		_aSabah Ahmed Mohamed _ethesis advisor.
900			_b01-01-2023 _cYosri Mohamed Kamel Akl _cYoussef Amin Soliman _cSabah Ahmed Mohamed _UCairo University _FFaculty of Medicine _DDepartment of pulmonary medicine
905			_aSara _eHuda
942			_2ddc _cTH _e21 _n0
999			_c170089