000			05411namaa22004211i 4500
003			OSt
005			20250423113613.0
008			250408s2024 ua a|||frm||| 000 0 eng d
040			_aEG-GICUC _beng _cEG-GICUC _dEG-GICUC _erda
041	0		_aeng _beng _bara
049			_aDeposit
082	0	4	_a616.8982
092			_a616.8982 _221
097			_aM.Sc
099			_aCai01.11.21.M.Sc.2024.Ma.A
100	0		_aMahinour Ahmed Tawfik Rezk, _epreparation.
245	1	0	_aAssociation between metabolic syndrome and neurocognitive and social cognitive functions in male patients with schizophrenia / _cby Mahinour Ahmed Tawfik Rezk ; Supervision Prof. Dr. Aref Abdel-Halim Khowailed, Dr. Walaa Amin Fakher.
246	1	5	_aالعلاقة بين متلازمة الأيض والوظائف المعرفية العصبية والاجتماعية في مرضى الفصام الذكور /
264		0	_c2024 .
300			_a222 pages : _billustrations ; _c25 cm. + _eCD.
336			_atext _2rda content
337			_aUnmediated _2rdamedia
338			_avolume _2rdacarrier
502			_aThesis (M.Sc)-Cairo University, 2024.
504			_aBibliography: pages 139-197.
520			_aBackground: Individuals with schizophrenia and metabolic disturbances exhibit impairments on multiple domains of social cognition (SC) and neurocognition which has been important target for intervention, with efforts aiming to improve early functional recovery. Aim: To assess neuro cognitive and social cognitive performance, the quantitative and qualitative difference of neuro cognitive performance and social cognitive performance, and the association between neuro cognitive performance and social cognitive performance and severity of metabolic disturbances among patients diagnosed with schizophrenia. Method: 60 patients with schizophrenia including metabolically healthy individuals, individuals with metabolic syndrome and individuals with metabolic disorder , patients were assessed by neuro-cognitive measures: Trail Making Test part A (TMT_A), digit span, digit symbol substitution and pair associate tests of Wechsler Adult Intelligence Scale (WAIS), and social cognitive measures: Reading Mind in the Eye Test (RMET) and Emotion Identification Test (Ekman). The patients' groups were assessed by the Positive and Negative Syndrome Scale for Schizophrenia (PANSS), metabolic parameters were assessed by waist circumference, TG, HDL, blood pressure and blood glucose level. Results: There was no statistically significant difference between schizophrenia patients with metabolic disturbances and schizophrenia patients with healthy metabolism in the scores of basic neuro-cognitive and social cognitive measures. For correlation there was statically significant positive correlation between using high doses and antipsychotics and metabolic syndrome. As regards PANNS_N scores, the study results show significant association between metabolic syndrome and severity of negative psychotic symptoms among patients diagnosed with schizophrenia. Conclusion: There is no quantitative or qualitative difference of neuro cognitive performance and social cognitive performance between patients diagnosed with schizophrenia with metabolic syndrome and patients with schizophrenia without metabolic syndrome.
520			_aالقصور المعرفي هو واحد من أهم أعراض الفصام. خاصة اضطراب الادراك المعرفي العصبي والاجتماعي الإدراك المعرفي الاجتماعي هو المجال المعرفي الذي يسهل التواصل الاجتماعي الفعال و بناء العلاقات بين الناس وبعضهم البعض، وتقوم هذه العملية العقلية المعقدة علي خطوات عدة مثل التعرف علي التغيرات في قسمات وجه الآخرين وتفسيرها، واستنباط المشاعر التي يشعر بها الأشخاص عبر تعابير الوجه المختلفة والخبرات السابقة، وهذا يساعد علي فهم الإشارات الاجتماعية العدة، ويساعد في النهاية علي التواصل بين الناس. هناك عوامل عدة تؤثر على الوظائف المعرفية. متلازمة الأيض واحدة من تلك العوامل. أثبتت الدراسات السابقة أن مرضى الفصام الذين يعانون من متلازمة الأيض يعانون من تأثر أكبر في الوظائف المعرفية من مرضى الفصام الذين لا يعانون من متلازمة الأيض. الاكتشاف والعلاج المبكر للمرضى ذوي الاحتمالية العالية لمتلازمة الأيض يساعد في تحسن استجابة المرضى للعلاج.
530			_aIssues also as CD.
546			_aText in English and abstract in Arabic & English.
650		7	_aSchizophrenia _2qrmak
653		0	_aSchizophrenia _ametabolic syndrome _aneurocognition _asocial cognition
700	0		_aAref Abdel-Halim Khowailed _ethesis advisor.
700	0		_aWalaa Amin Fakher _ethesis advisor.
900			_b01-01-2024 _cAref Abdel-Halim Khowailed _cWalaa Amin Fakher _UCairo University _FFaculty of Medicine _DDepartment of Psychiatry
905			_aShimaa _eEman Ghareb
942			_2ddc _cTH _e21 _n0
999			_c171361