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040			_aEG-GICUC _beng _cEG-GICUC _dEG-GICUC _erda
041	0		_aeng _beng _bara
049			_aDeposit
082	0	4	_a616.7223
092			_a616.7223 _221
097			_aPh.D
099			_aCai01.11.08.Ph.D.2024.Na.E
100	0		_aNada Hany Mohamed Elshamy, _epreparation.
245	1	0	_aEffect of life style modification on patients with knee osteoarthritis attending nrc rheumatology clinic / _cby Nada Hany Mohamed Elshamy ; Supervised Prof. Dr. Mona Soliman Mohamed, Prof. Dr. Rehab Abdelhai Ahmed, Prof. Dr. Iman Ibrahim Salama, Dr. Mennat Allah Said.
246	1	5	_aتأثير تعديل نمط الحياة على مرضى إلالتهاب العظمى المفصلى للركبة المترددين على عيادة الروماتيزم بالمركز القومى للبحوث /
264		0	_c2024.
300			_a161 pages : _billustrations ; _c25 cm. + _eCD.
336			_atext _2rda content
337			_aUnmediated _2rdamedia
338			_avolume _2rdacarrier
502			_aThesis (Ph.D)-Cairo University, 2024.
504			_aBibliography: pages 120-140.
520			_aBackground: Osteoarthritis (OA) is a degenerative joint disease, the most prevalent form of arthritis, affecting an estimated 302 million people worldwide. It is the fastest growing cause of disability driven by an increasingly older population and the growing incidence of obesity. Lifestyle changes are gaining increasing recognition in the management of osteoarthritis. In most guide-lines advice on education, exercise, and dietary weight management are now given priority over pharmacological therapies regardless of disease severity and co-morbidity. Objectives: 1. To assess risk factors, quality of life, severity of knee osteoarthritis, knowledge, attitude and practices among knee osteoarthritis patients. 2. To determine the relation between inflammatory biomarker IL-6 and severity of osteoarthritis. 3. To evaluate the effect of combined intervention of health, nutritional education and home-based exercise on severity of knee OA, patients' quality of life, knowledge, attitude and practice and IL-6. Methods: A prospective interventional study was done, where 180 KOA patients were consecutively recruited from the Rheumatology Outpatient Clinic at the National Research Centre. The patients were followed up for 6 months and reassessed after health education sessions and home-based exercise intervention using WOMAC, OAKHQOL, and KAP questionnaires. Results: More than half of the participants were between 51-60 years old (53.3%), 72.2% of them were females. Most of the participants had a university degree (40.6%) and 80.6% them worked in the administrative jobs. The mean of the BMI was 34.6±7.3. There was a highly significant improvement among KOA patients with a significant decrease in the total mean WOMAC score and increase in the total median OAKHQOL score and their domains after the intervention compared to the baseline score, p<0.001. A significant improvement in the total-knowledge score among the studied KOA patients was found, p<0.001. Conclusion: The severity of KOA symptoms, quality of life, and patients’ knowledge regarding KOA had statistically improved after health education and home-based exercise program intervention
520			_aيعتبر التهاب المفاصل من أكثر الأمراض انتشارا حيث يؤثر على ما يقدر بنحو 302 مليون شخص في جميع أنحاء العالم. وهو عبارة عن تدهور في حالة المفصل ككل بما في ذلك تدهور الغضاريف، وتغيير في شكل العظام، وظهور نتؤات عظمية، والالتهاب الزليلي مما يؤدي إلى فقدان وظيفة المفصل الطبيعية. يعتبر نمط الحياة الصحي عامل مهم في علاج مرض التهاب المفاصل ولذلك فإن معظم الإرشادات الصحية تنصح بممارسة الرياضة والتحكم فى الوزن وتعتبرهما علاجا أكثر أهمية من العلاجات الدوائية بغض النظر عن شدة المرض والأمراض المتزامنة معه. إن العلاج بممارسة الرياضة يعد واحدا من أهم العلاجات الغير دوائية وهو طريقة آمنة ومنخفضة التكلفة لعلاج التهاب المفاصل والذى ثبت أن له دور فى تأخير تطور المرض، وتخفيف الألم، وتحسين وظيفة الركبة عن طريق تقوية العضلات وتحسين التحكم العصبي العضلي ونطاق حركة المفصل في الركبة المصابة.
530			_aIssues also as CD.
546			_aText in English and abstract in Arabic & English.
650		7	_aOsteoarthritis _2qrmak
653		0	_aKOA _aWOMAC _aOAKHQOL _aKAP _aQuality of life- Health education _aHome-based exercise program
700	0		_aMona Soliman Mohamed _ethesis advisor.
700	0		_aRehab Abdelhai Ahmed _ethesis advisor.
700	0		_aIman Ibrahim Salama _ethesis advisor.
700	0		_aMennat Allah Said _ethesis advisor.
900			_b01-01-2024 _cMona Soliman Mohamed _cRehab Abdelhai Ahmed _cIman Ibrahim Salama _cMennat Allah Said _UCairo University _FFaculty of Medicine _DDepartment of Public Health
905			_aShimaa _eEman Ghareb
942			_2ddc _cTH _e21 _n0
999			_c172132