000 019710000a22003490004500
003 EG-GICUC
005 20250223024919.0
008 081225s2006 ua f m 000 0 eng d
040 _aEG-GICUC
_beng
_cEG-GICUC
041 0 _aEng
049 _aDeposite
097 _aPh.D
099 _aCai01.19.03.Ph.D.2006.Ma.C.
100 0 _aMahmoud Mohammad Kamel
245 1 0 _aChronic b - lymphocytic leukaemia : immunoregulatory molecules , antigen experienced b - cells , and nurse - like cells /
_cMahmoud Mohammad Kamel ; supervised Moushira Fathy Elseify , Maha Saleh Madbouly , Faten Hafez Elmahalawy
246 1 5 _aسرطان الدم المزمن بالجزيئات المنظمة للمناعة : الخلايا بالمجربة للانتجين والخلايا مثيلة الحاضنة
260 _aCairo :
_bMahmoud Mohammad Kamel ,
_c2006
300 _a216P ;
_c25cm
502 _aThesis (PH.D.) - Cairo University - National Cancer Institute - Department Of Clinical Pathology
520 _aGrowth and survival of chronic lymphocytic leukemia (CLL) B cells are favored by interactions between CLL and non tumoral accessory cellsInteraction between nurse - like cells (NLCs) and cells in vivo could help to sustain leukemia cell survival and mitigate the activity of drugs use to treat this disease The over expression of CD40 and CXCR4 and the defective expression of CD80 and CD86 in CLL patients mal be a major cause of growth , survival and failure of T - cell immunity against leukemic cells
530 _aIssued also as CD
653 4 _aAntigen - experienced B cells
653 4 _aChronic lymphocytic leukemia (CLL)
653 4 _aNurse - like cells (NLCs)
700 0 _aFaten Hafez Elmahalawy ,
_esupervisor
700 0 _aMaha Saleh Madbouly ,
_esupervisor
700 0 _aMoushira Fathy Elseify ,
_esupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aEnas
_eCataloger
905 _aMustafa
_eRevisor
942 _2ddc
_cTH
999 _c1737
_d1737