000 05228namaa22004451i 4500
003 EG-GICUC
005 20260302122931.0
008 260218s2025 ua a|||frm||| 000 0 eng d
040 _aEG-GICUC
_beng
_cEG-GICUC
_dEG-GICUC
_erda
041 0 _aeng
_beng
_bara
049 _aDeposit
082 0 4 _a615.321
092 _a615.321
_221
097 _aPh.D
099 _aCai01.07.04.Ph.D.2025.Az.B
100 0 _aAzza Emad Mostafa El-Ansary,
_epreparation.
245 1 0 _aBiological and technological evaluation of some special diets supplemented with some medicinal plants /
_cby Azza Emad Mostafa El-Ansary ; Supervisors: Dr. Ebtesam Abdel-Moniem Mahmoud, Dr. Sayed Abd ELKader Sayed Mohamed, Dr. Nadia Hossni Ali Assem.
246 1 5 _aالتقييم الحيوى والتكنولوجى لبعض الأنظمة الغذائية الخاصة المدعمة ببعض النباتات الطبية
264 0 _c2025.
300 _a132 pages :
_billustrations ;
_c25 cm. +
_eCD.
336 _atext
_2rda content
337 _aUnmediated
_2rdamedia
338 _avolume
_2rdacarrier
502 _aThesis (Ph.D)-Cairo University, 2025.
504 _aBibliography: pages 103-132.
520 3 _aThis study aimed to identify the phenolic compounds, investigate the antioxidant, antimicrobial, and anticancer activity of cinnamon, sumac or turmeric extracts; crude (ethanol) and successive extracts (petroleum ether, ethyl acetate and ethanol), synthesis of silver nanoparticles to study the physical characteristics and antioxidant, antimicrobial and anticancer activities of nanoparticles and produce cinnamon, sumac or turmeric crackers, comparing imbalanced diets with the crackers to increase their usefulness in resisting some of the side effects of these diets. The results demonstrated that the ethanolic and crude extracts gave the highest antioxidant activity using DPPH● (IC ranging from 0.631 to 0.895 50 μg/mL) and ABTS (IC ranging from 0.903 to 0.995 μg/mL). Cinnamon 50 ethanolic extract (CEE) contains the highest concentrations of cinnamic and salicylic acids, while, turmeric ethanolic extract (TEE) has the highest concentration of Gallic acid followed by sumac crude extract (SCE). Also, sumac ethanolic extract (SEE) has the highest antimicrobial activity against B. subtilis, S. aureus, P. aeruginosa and C. albicans, while CEE has the highest antimicrobial activity against A. fumigatus but SCE has the largest inhibition zone on E. coli; compared with other extracts. Turmeric crude extract (TCE) has the highest anticancer activity against (PC3) and (MCF7) cell lines (LC = 30.62 and 33.53 μg/mL, respectively), on the other hand, 50 TEE has the highest anticancer activity against (HCT116) cell line (LC = 50 27.81 μg/mL). Compared to crude turmeric extract, TNPs extract shows greater antioxidant, anticancer, and antibacterial activity. The results demonstrated that feeding with HF and HC diets exerts multifarious effects on liver weight, glucose, hemoglobin, cholesterol, triglyceride, LDL and ALT levels. Rats fed on cinnamon, sumac or turmeric-fortified crackers resisted some of the side effects associated with HF and HC diets.
520 3 _aالمستخلصات الإيثانولية والخام للكركم والقرفة والسماق أعطت أعلى نشاط مضاد للأكسدة باستخدام DPPH و ABTS. تميز مستخلص السماق الإيثانولي بأعلى نشاط ضد B. subtilis, S. aureus, P. aeruginosa and C. albicans ، بينما تميز مستخلص القرفة الإيثانولي بأعلى نشاط ضدA. fumigatus ، وتميز مستخلص السماق الخام بأكبر تثبيط على E. coli ؛ مقارنةً بالمستخلصات الأخرى. تميز مستخلص الكركم الخام بأعلى نشاط ضد خلايا (PC3) و(MCF7)، بينما تميز مستخلص الكركم الإيثانولي بأعلى نشاط ضد خلايا (HCT116). تبين ان اتباع نظام غذائي عالى الدهون او الكربوهيدرات له تأثيرات متعددة على وزن الكبد، وسكر الدم، والهيموغلوبين، والكوليسترول، والدهون الثلاثية، وLDL وAST. قاومت البسكويت المدعم بالكركم والسماق والقرفة بعض هذه التأثيرات.
530 _aIssues also as CD.
546 _aText in English and abstract in Arabic & English.
650 0 _aMedicinal plants
650 0 _aالنباتات الطبية
653 1 _aTurmeric
_asumac
_acinnamon
_aAg – NPs
_ahigh-fat diet
_ahigh-carbohydrate diet
_aالكركم
_aالسماق
700 0 _aEbtesam Abdel-Moniem Mahmoud
_ethesis advisor.
700 0 _aSayed Abd ELKader Sayed Mohamed
_ethesis advisor.
700 0 _aNadia Hossni Ali Assem
_ethesis advisor.
900 _b01-01-2025
_cEbtesam Abdel-Moniem Mahmoud
_cSayed Abd ELKader Sayed Mohamed
_cNadia Hossni Ali Assem
_UCairo University
_FFaculty of Agriculture
_DDepartment of Agricultural Biochemistry
905 _aShimaa
_eEman Ghareb
942 _2ddc
_cTH
_e21
_n0
999 _c178587