000 01598cam a2200277 a 4500
003 EG-GiCUC
005 20250223030221.0
008 100420s2009 ua h f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aGift
097 _aM.Sc
099 _aCai01.34.M.Sc.2009.Mo.D
100 0 _aMohamed Saleh Mohamed Ali
245 1 0 _aDesign synthesis and biological evaluation of novel tetrahydro - Ý - carboline derivatives as phosphodiesterase 5 inhibitors /
_cMohamed Saleh Mohamed Ali ; Supervised Ashraf H. Abadi
246 1 5 _aتصميم وتشييد بعض مشتقات البيتاكربولين وتقييمها بيولوجيا كمثبطات لإنزيم الفسفودايستراز5
260 _aCairo :
_bMohamed Saleh Mohamed Ali ,
_c2009
300 _a94 P. :
_bfacsimiles ;
_c30cm
502 _aThesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Science in Organic Chemistry
520 _aPDE5 inhibitors is a large class of compounds that are primarily used to treat erectile dysfunction (MED) as well as having other medical applications . Tadalafil is one of the most potent members among this class despite its efficacy in treatment of MED it only exhibits a modest selectivity of 5 - folds for PDE - 5 compareed PDE - 11 which may be involved in sperm formation motility and\ or other homonal functions
700 0 _aAshraf H. Abadi ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aFatma
_eCataloger
905 _aNazla
_eRevisor
942 _2ddc
_cTH
999 _c30051
_d30051