000 01923cam a2200349 a 4500
003 EG-GiCUC
005 20250223030337.0
008 110117s2010 ua h f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.08.04.Ph.D.2010.Af.S
100 0 _aAfaf Ali Atia Elmalah
245 1 0 _aSynthesis of certain fused thienopyridine derivatives of expected activity against alzheimer's disease /
_cAfaf Ali Atia Elmalah ; Supervised Mohga Mohamed Badran , Maha Abdelhakeem , Suzan Mohamed Abuelmaaty
246 1 5 _aتشييد بعض مركبات الثاينوبيريدين الملتحمة ذات نشاط متوقع ضد مرض الالزهيمر
260 _aCairo :
_bAfaf Ali Atia Elmalah ,
_c2010
300 _a120P. :
_bfacsimiles ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Organic Chemistry
520 _aA survey covering the methods used for the synthesis of thienopyridine derivatives in addition to their reactions is illustrated . Abrief outline on their medical importance is also given . This thesis involves the preparation of the starting compounds 2- amino - 3- cyanothiophene derivatives {u2161}a-c (scheme 1) . cyclodehydration reaction between the aminocyanothiophenes and the appropriate cyclanone was achieved by using two methods to obtain thienopyridine derivatives {u2162}a-c, IVa-c, {u2164}a-c, {u2165}I, {u2167} and IX(scheme 2- 4)
530 _aIssued also as CD
653 4 _aAlzheimer's disease
653 4 _aTacrine
653 4 _aThienopyridine derivatives
700 0 _aMaha Abdelhakeem ,
_eSupervisor
700 0 _aMohga Mohamed Badran ,
_eSupervisor
700 0 _aSuzan Mohamed Abuelmaaty ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSoheir
_eCataloger
942 _2ddc
_cTH
999 _c32720
_d32720