000 01752cam a2200349 a 4500
003 EG-GiCUC
005 20250223030654.0
008 120917s2012 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.11.07.Ph.D.2012.Al.A
100 0 _aAlaa Afif Abdelraouf
245 1 4 _aThe association between kir6.2 mutation and type 1 diabetes /
_cAlaa Afif Abdelraouf ; Supervised Nadida Abdelhamid Gohar , Shereen Abdelghaffar Taha , Nahla Aly Fawzy Fayek
246 1 5 _aالعلاقة بين التحور الجينى للجين ( كير 2و6 ) والنوع الاول من البول السكرى
260 _aCairo :
_bAlaa Afif Abdelraouf ,
_c2012
300 _a81Leaves :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology
520 _aThe pancreatic ATP - sensitive potassium ( Katp ) channel is a critical regulator of beta - cell insulin secretion . Heterozygous activating mutations in the KCNJ11 gene , which encodes the Kir 6.2 subunit of the Katp channel , have been found to cause diabetes in the neonatal period or early infancy . This molecular study hypothesized that KCNJ11 mutations could present clinically as type 1 diabetes
530 _aIssued also as CD
653 4 _aKatp channel
653 4 _akir6.2
653 4 _aNeonatal diabetes
700 0 _aNadida Abdelhamid Gohar ,
_eSupervisor
700 0 _aNahla Aly Fawzy Fayek ,
_eSupervisor
700 0 _aShereen Abdelghaffar Taha ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aFatma
_eCataloger
905 _aNazla
_eRevisor
942 _2ddc
_cTH
999 _c39529
_d39529