000 01847cam a2200349 a 4500
003 EG-GiCUC
005 20250223030719.0
008 121127s2012 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.11.03.Ph.D.2012.Ra.S
100 0 _aRania Elsayed Hussein Abdelrahman
245 1 0 _aSignaling mechanisms of water soluble curcumin derivative in diabetic cardiovascular complications /
_cRania Elsayed Hussein Abdelrahman ; Supervised Mohamed Talaat Abdelaziz , Dimitri Mikhailidis , Ibrahim Elibrashy
246 1 5 _aآليات عمل مشتق الكركم القابل للذوبان فى مضاعفات القلب و الأوعية الدموية لمرضى البول السكرى
260 _aCairo :
_bRania Elsayed Hussein Abdelrahman ,
_c2012
300 _a264 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of - Medical Biochemistry
520 _aCurcumin has been identified as a potent inducer of heme-oxygenase-1 (HO-1), protein that provides protection against various forms of stress. Diabetic cardiomyopathy characterized by cardiomyocyte hypertrophy, eventually leads to heart failure. Transcriptional co-activator p300 and its interaction with myocyte enhancer factor 2 (MEF2) play a major role in diabetes-induced cardiomyocyte hypertrophy
530 _aIssued also as CD
653 4 _aCurcumin
653 4 _aDiabetes type 1
653 4 _aDiabetic cardiomyopathy
700 0 _aDimitri Mikhailidis ,
_eSupervisor
700 0 _aIbrahim Elibrashy ,
_eSupervisor
700 0 _aMohamed Talaat Abdelaziz ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSamia
_eCataloger
942 _2ddc
_cTH
999 _c40387
_d40387