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008 130327s2009 ua d f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aGift
097 _aM.Sc
099 _aCai01.34.M.Sc.2009.Ay.O
100 0 _aAya Mohamed Abdelkader Serry
245 1 0 _aOne pot synthesis and biological evaluation of novel heterocyclic compounds /
_cAya Mohamed Abdelkader Serry ; Supervised Ashraf H. Abadi
246 1 5 _aالتشييد والتقييم البيولوجى لمركبات جديدة غير متجانسة الحلقة
260 _aCairo :
_bAya Mohamed Abdelkader Serry ,
_c2009
300 _a98Leaves :
_bcharts ;
_c30cm
502 _aThesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry
520 _aP38Ü mitogen activated protein kinase regulates the expression of inflammatory cytokines suggesting a role in the pathogenesis of diseases such as rheumatoid arthritis as well as cancer progression . Many heterocyclic compouds have been reported to posses p38 MAP kinase inhibitory properties however the main shortcoming for development into clinical candidates were toxicity and unselectivity towards other kinases
700 0 _aAshraf H. Mostafa Abadi ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSoheir
_eCataloger
942 _2ddc
_cTH
999 _c42283
_d42283