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008 130328s2011 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aGift
097 _aM.Sc
099 _aCai01.34.M.Sc.2011.No.S
100 0 _aNoha Hazem Mahmoud Ali Atta
245 1 0 _aSynthesis and biological evaluation of novel celecoxib analogues and their evaluation as cyclooxygenases and phosphodiesterase 5 inhibitors /
_cNoha Hazem Mahmoud Ali Atta ; Supervised Ashraf H. Abadi
246 1 5 _aالتشييد والتقييم البيولوجى من مشبهات السليكوكسيب وتقيمها كمثبطات انزيمات السيكلواوكسيجيناز والفوسفودايستراز5
260 _aCairo :
_bNoha Hazem Mahmoud Ali Atta ,
_c2011
300 _a82Leaves :
_bcharts , facsimiles ;
_c30cm
502 _aThesis (M.Sc.) - German University - Faculty of Postgraduate studies and scientific Research - Department of Pharmaceutical Chemistry
520 _aNon-selective cyclooxgenase (COX) inhibitors are effective anti-inflammatory agents . However , side effects such as gastric ulcers and abdominal pain have been reported . Selective cyclooxygenase-2 (COX-2) inhibitors have less gastric side effects but they were reported to increase the susceptibility of systemic hypertension and thromboembolic complication such as myocardial infarction
700 0 _aAshraf H. Abadi ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aFatma
_eCataloger
905 _aNazla
_eRevisor
942 _2ddc
_cTH
999 _c42298
_d42298