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| 008 | 130330s2010 ua d f m 000 0 eng d | ||
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_aEG-GiCUC _beng _cEG-GiCUC |
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| 041 | 0 | _aeng | |
| 049 | _aGift | ||
| 097 | _aM.Sc | ||
| 099 | _aCai01.34.M.Sc.2010.He.S | ||
| 100 | 0 | _aHeba Abdulla Mohamed | |
| 245 | 1 | 0 |
_aSynthesis of novel heterocyclic compounds and their biological evaluation as phosphodiesterase inhibitors and anticancer agents / _cHeba Abdulla Mohamed ; Supervised Ashraf H. Abadi |
| 246 | 1 | 5 | _aتشييد مركبات جديدة غير متجانسة الحلقة و دراسة تأثيراتها الحيوية كمثبطات للإنزيم فوسفودايستريز و كعقاقير مضادة للسرطان |
| 260 |
_aCairo : _bHeba Abdulla Mohamed , _c2010 |
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| 300 |
_a139 Leaves : _bcharts ; _c30cm |
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| 502 | _aThesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry | ||
| 520 | _aTadalafil is an orally administered drug used to treat male erectile dysfunction (impotence). It is a Ý-carboline derivative that inhibits PDE 5, leading to elevation of cGMP, vascular relaxation in the corpora cavernosa and penile erection during sexual stimulation. Recently, studies have shown that phosphodiesterases including PDE5 are overexpressed in malignant tumors | ||
| 700 | 0 |
_aAshraf Mostafa Abadi , _eSupervisor |
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| 856 | _uhttp://172.23.153.220/th.pdf | ||
| 905 |
_aNazla _eRevisor |
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| 905 |
_aSamia _eCataloger |
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| 942 |
_2ddc _cTH |
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| 999 |
_c42319 _d42319 |
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