000 01525cam a2200277 a 4500
003 EG-GiCUC
005 20250223030816.0
008 130331s2010 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aGift
097 _aM.Sc
099 _aCai01.34.M.Sc.2010.Sh.S
100 0 _aShaimaa Awadain Elsharif
245 1 0 _aSynthesis of novel diary I heterocycle derivatives and their evaluation as growth inhibitory agents and phosphodiesterase 3 inhibitors /
_cShaimaa Awadain Elsharif ; Supervised Ashraf H. Abadi
246 1 5 _aتشييد مشتقات جديدة لثنائى ارايل غير متجانس الحلقة وتقيم قدرتهم كمثبطات النمو ومنع نشاط الفوسفوداى استراز 3
260 _aCairo :
_bShaimaa Awadain Elsharif ,
_c2010
300 _a90Leaves :
_bcharts , facsimiles ;
_c30cm
502 _aThesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical chemistry
520 _aMilrinone is a cyanopyridone derivative that has been introduced for the treatment of CHF . Its mechanism of action involves inhibition of PDE3 leading to elevation of cAMP increasing the entry of Ca⁺⁺ ions into the cardiac tissues and hence increasing the contractility of the cardiac muscle
700 0 _aAshraf H. Abadi ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSoheir
_eCataloger
942 _2ddc
_cTH
999 _c42368
_d42368