000 01536cam a2200289 a 4500
003 EG-GiCUC
005 20250223030816.0
008 130401s2010 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aGift
097 _aM.Sc
099 _aCai01.34.M.Sc.2010.Ya.E
100 0 _aYasmine Magdy Mandour
245 1 0 _aEvaluating the role of molecular polar surface area on cell permeation :
_bA multivariate model /
_cYasmine Magdy Mandour ; Supervised Stefan Laufer , Raimund Niess , Thomas Scior
260 _aCairo :
_bYasmine Magdy Mandour ,
_c2010
300 _a142Leaves :
_bcharts , facsimiles ;
_c30cm
502 _aThesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry
520 _aRecent drug design strategies consider the pharmacokinetic properties of drug candidates at early stages of drug development prior to any clinical trials . For some years , many in silico ADME screens have been developed . Polar surfce area (PSA) has been a very popular descriptor for the prediction of drug absorption . This descriptor seems to encode an optimal combination of hydrogen bonding features , molecular polarity and solubility properties
700 0 _aRaimund Niess ,
_eSupervisor
700 0 _aStefan Laufer ,
_eSupervisor
700 0 _aThomas Scior ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aFatma
_eCataloger
905 _aNazla
_eRevisor
942 _2ddc
_cTH
999 _c42375
_d42375