000 02059cam a2200337 a 4500
003 EG-GiCUC
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008 150210s2014 ua h f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.18.M.Sc.2014.Ra.C
100 0 _aRasha Hassan Mohamed Kotb
245 1 0 _aCorrelation between degree of hepatic fibrosis by liver biopsy and insulin resistance in chronic hepatitis C /
_cRasha Hassan Mohamed Kotb ; Supervised Emad Mohamed Almoetasm ,Yasser Bakr Mohamed
246 1 5 _aدراسة للعلاقة بين نسبة التليف الكبدي بالعينه الكبديه ونسبة مقاومة الانسولين في مرضى فيرس سي
260 _aCairo :
_bRasha Hassan Mohamed Kotb ,
_c2014
300 _a202 P. :
_bfacsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Internal Medicine
520 _a Insulin resistance (IR) occurs early in HCV infection and may affects liver fibrosis progression, treatment response and synergizes development of HCC. We thus studied prevalence of IR in HCV patients and correlation between IR and hepatic fibrosis. Fifty HCV, non diabetic patient were enrolled; Quantitative HCV RNA was assayed by PCR, histological assessment by liver biopsy was done and IR index assessed by using HOMA-IR, and an index value {u2265} 2.5 was designated IR and 10 normal subjects were studied as control. In this study prevalence of IR was 38% vs 62% p = 0.005, there is significant correlation between IR and hepatic fibrosis and inflammatory activity
530 _aIssued also as CD
653 4 _aHCV: hepatitis C virus
653 4 _aHOMA-IR:homeostasis model assessment-IR
653 4 _aIR: insulin resistance
700 0 _aEmad Mohamed Almoetasm ,
_eSupervisor
700 0 _aYasser Bakr Mohamed ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aAml
_eCataloger
905 _aNazla
_eRevisor
942 _2ddc
_cTH
999 _c49285
_d49285