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003 EG-GiCUC
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008 150210s2014 ua do f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.08.09.M.Sc.2014.Ho.S
100 0 _aHoda Samir Badr
245 1 0 _aStudy of the possible protective effect (s) of certain antioxidants against cadmium induced teratogenicity in experimental animals /
_cHoda Samir Badr ; Supervised Afaf A. Ain Shoka , Asmaa M. Kandil , Noha N. Nassar
246 1 5 _aدراسة التأثيرات المحتملة لبعض مضادات الاكسدة فى تشوهات الأجنة المحدثه من عنصر الكادميوم فى حيوانات التجارب
260 _aCairo :
_bHoda Samir Badr ,
_c2014
300 _a195 P. :
_bcharts , photographs ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmacology and Toxicology
520 _aThis work investigates the possible protective role of curcumin and selenium (Se), considered as antioxidants, singly or in combination in ameliorating cadmium (Cd) induced teratogenicity. Cadmium (18.4mg / kg, p.o) was given from day 7 to 16 of gestation. Curcumin (50mg / kg, p.o), Se (18æg / Kg, p.o) or their combination were administered all over the period of gestation with or without Cd insult. The results showed decrease in maternal body weight gain, increase in the rate of abortion, resorption and growth retardation of fetuses and malformations in their skeleton in group received Cd. Besides, there were significant decrease in red blood cells, and hemoglobin concentration while increase in the white blood cells count. Serum levels of AST, ALT, LDH, urea and creatinine showed significant elevation in mothers and their fetuses compared to the normal control group
530 _aIssued also as CD
653 4 _aCadmium
653 4 _aCurcumin
653 4 _aSelenium
700 0 _aAfaf Abdelmonem Ain Shoka ,
_eSupervisor
700 0 _aAsmaa Monir Kandil ,
_eSupervisor
700 0 _aNoha Nagah Nassar ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSamia
_eCataloger
942 _2ddc
_cTH
999 _c49290
_d49290