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003 EG-GiCUC
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008 150323s2014 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.09.04.Ph.D.2014.Sa.A
100 0 _aSara Mohammed Abdelwahed
245 1 0 _aAssessment of DNA content by flow cytometry and immunohistochemical expression of BUBR1 in oral epithelial dysplastic Lesions /
_cSara Mohammed Abdelwahed ; Supervised Naglaa Mohamed Elhossary , Safa Fathy Abdelghani , Abeer Mostafa Elsayed
246 1 5 _aفى آفات خلل التنسج الطلائى الفمىBUBRIتقييم محتوى الحمض النووى بواسطة التدفق الخلوى وإظهار المناعة الهيستوكيميائية لل
260 _aCairo :
_bSara Mohammed Abdelwahed ,
_c2014
300 _a115 Leaves :
_bcharts , facsimiles ;
_c30cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Oral Pathology
520 _aOral epithelial dysplasia represents a relatively late phase in the multistage process of oral carcinogenesis, which is one of the most frequent cancers in the world. Accordingly, our goal was to assess the DNA ploidy status and the immunohistochemical expression of BUBR1 in oral epithelial dysplasia and oral squamous cell carcinoma, correlation of our results with the histopathological findings and evaluation of their diagnostic and prognostic significance. Forty paraffin blocks were investigated and divided into: low and high risk dysplasia, well, moderately and poorly differentiated squamous cell carcinoma. Flow cytometry was used to evaluate the ploidy status, DNA index and S-phase fraction. Immunohistochemical expression of BUBR1 and the area percentage of the positive cells were detected
530 _aIssued also as CD
653 4 _aDNA ploidy
653 4 _aOral epithelial dysplasia
653 4 _aOral squamous cell carcinoma
700 0 _aAbeer Mostafa Elsayed ,
_eSupervisor
700 0 _aNaglaa Mohamed Elhossary ,
_eSupervisor
700 0 _aSafa Fathy Abdelghani ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aAml
_eCataloger
905 _aNazla
_eRevisor
942 _2ddc
_cTH
999 _c50014
_d50014