000 02269cam a2200349 a 4500
003 EG-GiCUC
005 20250223031208.0
008 150402s2014 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.10.10.Ph.D.2014.Em.S
100 0 _aEman Mohamed Samy Ahmed Elnaggar
245 1 0 _aStudy of the immunopotentiation effect of Esat-6 of mycobacteria on DNA vaccine encoding the H5 gene of avian influenza virus /
_cEman Mohamed Samy Ahmed Elnaggar ; Supervised Salah Eldien Abdelkarim Selim , Mohamed Ali Mohamed Elhady , Fakreya Abdelhafez Albordeny
246 1 5 _aلميكروب السل على لقاح الحامض النووى المشفر لجين H5 لفيروس انفلونزا الطيور Esat-6 دراسة على التأثير المناعى المحفز
260 _aCairo :
_bEman Mohamed Samy Ahmed Elnaggar ,
_c2014
300 _a281 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Veterinary Medicine - Department of Microbiology
520 _aIn the current study , the DNA vaccine coding for H5 gene of HPA1 H%N1 subtype was produced and co-administrated with DNA vaccine coding for esat6 gene of Mycobacteria (pcDNA3.1/esat6) as an immunomodulatore. first, samples taken from different governorates during 2010 and 2011 were subjected to extensive virus isolation and identification one of 2011 were subjected to extensive virus isolation and identification one of the isolated feed isolate was subjected for further investigation where the full length H5 gene was amplifed and sequenced and cloned in pENTER/D/SD/Topo entry clone and homologues recombination with pDEST40 mammalian expression destination vector was done to produce the DNA vaccine pDEST40/H5
530 _aIssued also as CD
653 4 _aDNA vaccine encoding
653 4 _aH5 gene
653 4 _aImmunopotentiation
700 0 _aFakreya Abdelhafez Albordeny ,
_eSupervisor
700 0 _aMohamed Ali Mohamed Elhady ,
_eSupervisor
700 0 _aSalah Eldien Abdelkarim Selim ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aAml
_eCataloger
905 _aNazla
_eRevisor
942 _2ddc
_cTH
999 _c50243
_d50243