| 000 | 02507cam a2200349 a 4500 | ||
|---|---|---|---|
| 003 | EG-GiCUC | ||
| 005 | 20250223031208.0 | ||
| 008 | 150404s2014 ua dh f m 000 0 eng d | ||
| 040 |
_aEG-GiCUC _beng _cEG-GiCUC |
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| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aPh.D | ||
| 099 | _aCai01.12.04.Ph.D.2014.He.N | ||
| 100 | 0 | _aHeba Mohamed Fahmy Abdelbaky | |
| 245 | 1 | 0 |
_aNeurobehavioral study on an animal model of multiple sclerosis / _cHeba Mohamed Fahmy Abdelbaky ; Supervised Anwar Abdelazim Elsayed , Nasr Mahmoud Radwan , Neveen Amin Noor |
| 246 | 1 | 5 | _aدراسة السلوك العصبى على نموذج حيوانى لمرض التصلب المتعدد |
| 260 |
_aCairo : _bHeba Mohamed Fahmy Abdelbaky , _c2014 |
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| 300 |
_a147 Leaves : _bcharts , facsimiles ; _c25cm |
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| 502 | _aThesis (Ph.D.) - Cairo University - Faculty of Science - Department of Biophysics | ||
| 520 | _aMultiple sclerosis (MS) is an immune mediated, inflammatory demyelinating neurodegenerative disease of the central nervous system (CNS). Experimental autoimmune encephalomyelitis (EAE) is a well- established animal model of MS. The aim of the present study is to investigate the protective and therapeutic effects of Nigella sativa (N. sativa) seeds (2.8 g / kg body weight) in EAE-induced rats. EAE was induced by single subcutaneous injection in the tail base with 100 æg myelin oligodendrocyte glycoprotein (MOG) in complete Freund's adjuvant (CFA) containing 1 mg / ml of Mycobacterium tuberculosis. Animals immunized with MOG were divided into 3 groups: 1- EAE-induced animals (2EAE3 group) received daily oral administration of distilled water until the end of the experiment. 2- The animals of the second group (2N. sativa + EAE3 group) received daily oral administration of N. sativa 2 weeks prior EAE induction till the end of the experiment. 3- Animals of the third group (2EAE + N. sativa3 group) received daily oral administration of N. sativa after the appearance of first clinical signs until the end of the experiment | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aDemyelination | |
| 653 | 4 | _aExperimental autoimmune encephalomyelitis (EAE) | |
| 653 | 4 | _aNigella sativa (N.sativa) | |
| 700 | 0 |
_aAnwar Abdelazim Elsayed , _eSupervisor |
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| 700 | 0 |
_aNasr Mahmoud Radwan , _eSupervisor |
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| 700 | 0 |
_aNeveen Amin Noor , _eSupervisor |
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| 856 | _uhttp://172.23.153.220/th.pdf | ||
| 905 |
_aNazla _eRevisor |
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| 905 |
_aSoheir _eCataloger |
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| 942 |
_2ddc _cTH |
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_c50258 _d50258 |
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