000 02429cam a2200337 a 4500
003 EG-GiCUC
005 20250223031217.0
008 150421s2014 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.12.04.Ph.D.2014.Em.A
100 0 _aEman Ali Eldin Ali Abdelfatah
245 1 0 _aAssessment of the therapeutic efficacy of curcumin {u2013}loaded Nanoparticles as a natural anticancer agent /
_cEman Ali Eldin Ali Abdelfatah ; Supervised Wafaa A. Khalil , Nihal S. El-Bialy
246 1 5 _aتقييم الكفاءة العلاجية للكركم محمل على جزيئات نانومترية كمضاد طبيعى للسرطان
260 _aCairo :
_bEman Ali Eldin Ali Abdelfatah ,
_c2014
300 _a159 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Science - Department of Biophysics
520 _aCancer is a lethal disease caused by damage in the genetic material (i.e. DNA) which leads to uncontrollable cell division. Chemotherapy is one of the three main methods of cancer treatment including surgical interference and radiotherapy. Chemotherapy is characterized with its applicability to all types and stages of cancer. The major problem associated with chemotherapy is the inability to deliver pharmaceuticals to a specific site of the body without inducing normal tissue toxicity. As a consequence, the development of an alternative modalities using {u2018}Natural anticancer agents{u2019} open up new avenue for future cancer therapy due to their safety. Curcumin is one of the most promising natural anticancer agents, however, its medical application has been limited by its poor water solubility and bioavailability. Attempts have been made to encapsulate curcumin in different carriers, but the interest in nanocarriers for cancer chemotherapy is growing to develop a biodegradable controlled drug delivery vehicles that improve the bioavailability and solubility of curcumin
530 _aIssued also as CD
653 4 _aCurcumin
653 4 _aLoaded Nanoparticles
653 4 _aNatural anticancer
700 0 _aNihal S. El-Bialy ,
_eSupervisor
700 0 _aWafaa A. Khalil ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSoheir
_eCataloger
942 _2ddc
_cTH
999 _c50542
_d50542