000 02024cam a2200349 a 4500
003 EG-GiCUC
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008 150512s2014 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.11.28.Ph.D.2014.Mo.O
100 0 _aMohammed Gamal Eldin Fathallah
245 1 0 _aOcular manifestations of nephropathic cystinosi /
_cMohammed Gamal Eldin Fathallah ; Supervised Neveen Abdelmonem Soliman , Akmal Abdelmonem Rizk , Ahmed Mohamed Badr
246 1 5 _aدراسة تأثر العين فى مرض السيستينوسيس الكلوى
260 _aCairo :
_bMohammed Gamal Eldin Fathallah ,
_c2014
300 _a143 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pediatrics
520 _aBackground: Nephropathic cystinosis is a rare genetic disease characterized by accumulation of the amino acid cystine in lysosomes throughout the body. Ocular manifestations, particularly corneal cystine crystal formation, remain a major complication of nephropathic cystinosis.Conclusion: Anterior segment ocular manifestations of nephropathic cystinosis are more frequent than posterior segment involvement, being uniformly present in almost all patients beyond infancy. Topical cysteamine therapy is effective in depleting cystine crystals from the avascular cornea. Nevertheless, there is a pressing need for long-acting cysteamine eye drops to enhance patient compliance and improve outcome
530 _aIssued also as CD
653 4 _aCorneal cystine crystal scoring
653 4 _aCysteamine eye drops
653 4 _aNephropathic cystinosis
700 0 _aAhmed Mohamed Badr ,
_eSupervisor
700 0 _aAkmal Abdelmonem Rizk ,
_eSupervisor
700 0 _aNeveen Abdelmonem Soliman ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSoheir
_eCataloger
942 _2ddc
_cTH
999 _c50891
_d50891