000 02779cam a2200349 a 4500
003 EG-GiCUC
005 20250223031228.0
008 150516s2014 ua d f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.08.03.Ph.D.2014.Ay.A
100 0 _aAyman Mohamed Abdelaziz Mohsen
245 1 0 _aAnalytical study of some antihistaminic drugs /
_cAyman Mohamed Abdelaziz Mohsen ; Supervised Sonia Zaki Elkhateeb , Mostafa Abdelaty Shehata , Amr Mohamed Badawey
246 1 5 _aدرا{uئإآ٣}{uئإ٩٤} {uئإ٩٧}{uئإء٣}{uئإإ٠}{uئآئإ}{uئإإ٠}{uئآئإ}{uئإ٩٤} {uئإؤئ}{uئإ٩١}{uئإأأ}ض ا{uئإئ٧}دو{uئآئإ}{uئإ٩٤} ا{uئإؤئ}{uئإإ٣}{uئإآئ}{uئإ٨إ}دة {uئإؤئ}{uئإإ٠}{uئآءؤ}{uئإآ٣}{uئإ٩٧}{uئإ٨إ}{uئإإ٣}{uئآئإ}ن
260 _aCairo :
_bAyman Mohamed Abdel Aziz Mohsen ,
_c2014
300 _a346 P. :
_bcharts ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Analytical Chemistry
520 _aAn antihistamine is a pharmaceutical drug that inhibits the action of histamine by either blocking its attachment to histamine receptors,or inhibiting the enzymatic activity of histidine decarboxylase which catalyzes the transformation of histidine into histamine. Histamine produces increased vascular permeability, causing fluid to escape from capillaries into tissues, which leads to the classic symptoms of an allergic reaction. This thesis is concerned with the analysis of two antihistaminic drugs (namely chlorphenoxamine hydrochloride and chlorpheniramine maleate) in 3 pharmaceutical preparations utilizing a total of 13 different spectrophotometric methods. They are marketed in combination with other pharmaceutically active drugs which are mainly used for the treatment of common cold, congestion, runny nose and watery eyes. A major problem in pharmaceutical analysis is the simultaneous determination of the active ingredients of multi component mixtures in presence of other components in the formulation such as excipients and additives by rapid, accurate and reliable methods.The conventional methods of analysis involving extraction or prior separation are usually tedious and time and resources consuming
530 _aIssued also as CD
653 4 _aColor
653 4 _aFinishing techniques
653 4 _aSurface roughness
700 0 _aAmr Mohamed Badawey ,
_eSupervisor
700 0 _aMostafa Abdelaty Shehata ,
_eSupervisor
700 0 _aSonia Zaki Elkhateeb ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSoheir
_eCataloger
942 _2ddc
_cTH
999 _c50920
_d50920