| 000 | 02705cam a2200337 a 4500 | ||
|---|---|---|---|
| 003 | EG-GiCUC | ||
| 005 | 20250223031242.0 | ||
| 008 | 150627s2014 ua dh f m 000 0 eng d | ||
| 040 |
_aEG-GiCUC _beng _cEG-GiCUC |
||
| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aM.Sc | ||
| 099 | _aCai01.09.08.M.Sc.2014.He.D | ||
| 100 | 0 | _aHeba Mostafa Abdelhakim Gamal Eldin | |
| 245 | 1 | 0 |
_aDetection of cathepsin C gene mutation and presenting a preventive periodontal regimen for patients suspected to have papillon lefevre syndrome / _cHeba Mostafa Abdelhakim Gamaleldin ; Supervised Mona Shoeib , Hala Nasr Soliman |
| 246 | 1 | 5 | _aالكشف عن طفرة بجين الكاثيبسين سى وتقديم نظام علاجى ووقائى للثة للمرضى المشتبة فى انهم يعانوا من متلازمة بابيون ليفيفر |
| 260 |
_aCairo : _bHeba Mostafa Abdelhakim Gamal Eldin , _c2014 |
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| 300 |
_a151 P. : _bcharts , facsimiles ; _c30cm |
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| 502 | _aThesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Periodontology | ||
| 520 | _aThe primary aim of this study was to confirm the diagnosis for those patients suspected to have Papillon Lefevre syndrome based upon clinical diagnosis by carrying out mutation analysis of Cathepsin C gene of the patients and their unaffected family members. We have examined four families with Papillon Lefevre syndromeWe have examined four families with Papillon Lefevre syndrome, and evaluated the gene encoding cathepsin C for mutations. The mutation detection strategy consisted of polymerase chain reaction amplification of all seven exons and flanking intronic sequences, followed by direct nucleotide sequencing. Sequence analysis of the 7 cases revealed the presence of mutations in all the seven patients. Our second aim was to review the different periodontal regimens and evaluate the effect of a comprehensive preventive program, based on mechanical plaque control and systemic antibacterial measures, on periodontal health and preservation of teeth in PLS patients. According to the evaluation of the periodontal recordings, deterioration of the periodontal status was inevitable in case 1 while in case 2 the periodontal status was maintained more or less stable over the two-year period of the study | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aCathepsin C gene | |
| 653 | 4 | _aPapillon Lefevre Syndrome | |
| 653 | 4 | _aPreventive periodontal regimen | |
| 700 | 0 |
_aHala Nasr Soliman , _eSupervisor |
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| 700 | 0 |
_aMona Shoeib , _eSupervisor |
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| 856 | _uhttp://172.23.153.220/th.pdf | ||
| 905 |
_aNazla _eRevisor |
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| 905 |
_aSoheir _eCataloger |
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| 942 |
_2ddc _cTH |
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| 999 |
_c51439 _d51439 |
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