000 03032cam a2200349 a 4500
003 EG-GiCUC
005 20250223031331.0
008 151108s2015 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.07.10.M.Sc.2015.Sa.G
100 0 _aSara Mohamed Abdelghany
245 1 0 _aGenetic studies on growth hormone as a physiological indicator in rabbits /
_cSara Mohamed Abdelghany ; Supervised Abdelkader Yousef Gamal Eldin , Basita Abbas Hussein , Yaser Kamel Badawi
246 1 5 _a دراسات وراثية على هرمون النمو كمؤثر فسيولوجي في الارانب
260 _aCairo :
_bSara Mohamed Abdelghany ,
_c2015
300 _a89 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Agriculture - Department of Genetics
520 _aThe aim of the present study was to evaluate the effects of GH gene polymorphisms on reproduction and growth traits and identify its variability in the rabbits. A total of 218 blood samples collected from rabbits were used to evaluate the allele frequency distribution for GH gene polymorphisms and its association with reproductive and growth traits in rabbits. The samples included 16 rabbits of the different breeds (Middle-Egypt native breed, Gabali Sinai, Baladi Black, Baladi Red and New Zealand White) and 202 rabbits (118 {u2640} and 84 {u2642}) from APRI rabbits. The traits tested were: (1) body weight (BW) at 5, 6, 8,10 and 12 weeks from birth, (2) daily bodyweight gain (DBG), (3) reproductive traits included age at puberty (AP), Kindling interval (KI), litter size at birth (LS), litter weight (LW) at birth, Litter size at weaning (LSW) and litter weaning (LWW), (4) milk yield. For this purpose, DNA was extracted from rabbit blood samples and used in PCR amplification. The c.-78C >T SNP was genotyped by PCR-RFLP using the digestion by restriction enzyme Bsh1236I (BstUI). Association analysis between the GH C >T SNP and body weight, growth and reproductive traits was tested in the rabbits population using SAS program. The heterozygous genotype was associated with heavy weight of rabbits in different ages during the growth period. This increase in weight was significant (P < 0.05) at 8 weeks of age. DBG through 5-8 week interval was significantly associated (P < 0.05) with the T/C genotype. The heterozygous genotype (T/C) exhibited higher values in the DG compared to C/C and T/T genotypes. The estimated dominant genetic effect (d) was significant (P < 0.05) in 8 weeks
530 _aIssued also as CD
653 4 _aAssociation study SNP
653 4 _aGH
653 4 _aRabbit
700 0 _aAbdelkader Yousef Gamal Eldin ,
_eSupervisor
700 0 _aBasita Abbas Hussein ,
_eSupervisor
700 0 _aYaser Kamel Badawi ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSoheir
_eCataloger
942 _2ddc
_cTH
999 _c53154
_d53154