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008 151118s2015 ua h f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.08.06.M.Sc.2015.Sa.S
100 0 _aSally Atef Mohamed
245 1 2 _aA study of the role of interaction between moraxella catarrhalis surface antigens and the specific host antibody response on the occurrence of otitis media /
_cSally Atef Mohamed ; Supervised Aisha Abdelaziz Salama , Ahmed Sherif Attia ,Tamer Ibrahim Mahmoud
246 1 5 _aدراسة عن دور التفاعل بين مولدات المضادات السطحية لميكروب الموراكسيلا كاتاراليس واستجابة العائل بالأجسام المضادة النوعية فى حدوث التهاب الأذن الوسطى
260 _aCairo :
_bSally Atef Mohamed ,
_c2015
300 _a120 P. :
_bfacsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Microbiology and Immunology
520 _aM. catarrhalis is human-restricted, gram negative diplococci. During the last 30 years, the acceptance of the idea that this bacterium being a true respiratory tract pathogen has increased; it accounts for nearly 20% of the acute otitis media cases in children. In this study, we have tried to investigate the association between the presence of certain M. catarrhalis virulence factors and the incidence of otitis media infections especially among Egyptian children. We have collected 81 nasal swabs from otitis media children and 37 nasal swabs from non-otitis media ones and identifying M. catarrhalis among them. The identification results showed that M. catarrhalis was present in 21 (26%) of the otitis media samples and 19 (51.5%) of the non-otitis media ones. Then investigating the presence of some of the genes encoding for some of the important virulence factors. The results showed that the gene encoding for OMP CD was significantly higher in the otitis media isolates than the non-otitis media ones. The rest of the virulence genes under study were generally higher in the otitis media isolates
530 _aIssued also as CD
653 4 _aMoraxella catarrhalis
653 4 _aOtitis media
653 4 _aVirulence factors
700 0 _aAhmed Sherif Attia ,
_eSupervisor
700 0 _aAisha Abdelaziz Salama ,
_eSupervisor
700 0 _aTamer Ibrahim Mahmoud ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aAml
_eCataloger
905 _aNazla
_eRevisor
942 _2ddc
_cTH
999 _c53380
_d53380