| 000 | 03435cam a2200349 a 4500 | ||
|---|---|---|---|
| 003 | EG-GiCUC | ||
| 005 | 20250223031350.0 | ||
| 008 | 151207s2015 ua dh f m 000 0 eng d | ||
| 040 |
_aEG-GiCUC _beng _cEG-GiCUC |
||
| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aPh.D | ||
| 099 | _aCai01.11.20.Ph.D.2015.Mo.V | ||
| 100 | 0 | _aMona Mostafa Farid | |
| 245 | 1 | 0 |
_aVitamin D and its receptor gene polymorphism in ischemic vascular dementia : _bClinical, laboratory and genetic study / _cMona Mostafa Farid ; Supervised Ahmed Talaat Alghoneimy , Azza Abbas Helmy , Hala Mohamed Raslan |
| 246 | 1 | 5 |
_a{uFB70}{uFBFF}{uFE98}{uFE8E}{uFEE3}{uFBFF}{uFEE6} د و{uئإ٩٧}{uئإأأ}{uئإءء}د ا{uئإؤئ}{uئإآ٨}{uئإؤأ}{uئإؤإ} ا{uئإؤئ}{uئآ٧ؤ}{uئآئئ}{uئإإ٨}{uئإئ٢} {uئإؤئ}{uئإإ٤}{uئإآ٤}{uئإ٩٨}{uئإؤ٨}{uئإ٩٢}{uئإئأ}{uئإ٩٧}{uئآءآ} {uئإؤ٣}{uئإئ٠} ا{uئإؤئ}{uئإء٨}{uئإءإ}ف ا{uئإؤئ}{uئإإإ}{uئإأآ}{uئإ٨إ}{uئإ٨آ}{uئإئ٠} ا{uئإؤئ}{uئإإ٨}{uئإ٨إ}{uئإ٩٧}{uئإ٩إ} {uئإأآ}{uئإإ٦} ا{uئإؤئ}{uئإؤ٨}{uئإآأ}{uئإإإ}ر ا{uئإئ٩}ر{uئإ٩٧}{uئإإإ}ا{uئإ٨آ}{uئإئ٠} : _bدرا{uئإآ٣}{uئآءآ} ا{uئإؤآ}{uئإإ٠}{uئآئئ}{uئإإ٨}{uئآئئ}{uئإؤأ}{uئآئئ}{uئآءآ} : {uئإإ٣}{uئإأأ}{uئإإ٤}{uئإإ٠}{uئآئئ}{uئآءآ} و {uئإ٩ئ}{uئآئئ}{uئإإ٨}{uئآئئ}{uئآءآ} |
| 260 |
_aCairo : _bMona Mostafa Farid , _c2015 |
||
| 300 |
_a146 P. : _bcharts , facsimiles ; _c25cm |
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| 502 | _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Neurosurgery | ||
| 520 | _aIt was observed that vitamin D deficiency and vitamin D receptor gene polymorphism can influence cognitive performance. Aim: To study the relation between serum vitamin D level, vitamin D receptor gene polymorphism (Apa-l & Taq-l) and cognitive performance in ischemic stroke without dementia, ischemic vascular dementia & controls. Results: Vitamin D significantly affects cognitive performance in controls, including, total score of Addenbrooke's Cognitive Examination Revised (p 0.01), Story A from logical memory subtest of the Wechsler Memory Scale Revised (p>0.001), Paired Associate Learning Test (p>0.001) & Paced Auditory Serial Addition Test (p>0.001). PTH affects cognition in ischemic vascular dementia and controls but not ischemic stroke. Significantly different Taq-I alleles, (P =0.02) and genotypes (p= 0.009) distribution between studied groups. Apa-I genotypes polymorphisms were associated with cognitive performance. Conclusion: Vitamin D play an important role in preserving cognitive function of normal aging but cannot overcome the vascular burden of ischemic stroke or ischemic vascular dementia. Taq-I polymorphisms hypothesized to be associated with ischemic stroke and ischemic vascular dementia risks, while Apa-I polymorphisms hypothesized to be associated with cognitive performance | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aCognition | |
| 653 | 4 | _aIschemic stroke | |
| 653 | 4 | _aVitamin D | |
| 700 | 0 |
_aAhmed Talaat Alghoneimy , _eSupervisor |
|
| 700 | 0 |
_aAzza Abbas Helmy , _eSupervisor |
|
| 700 | 0 |
_aHala Mohamed Raslan , _eSupervisor |
|
| 856 | _uhttp://172.23.153.220/th.pdf | ||
| 905 |
_aNazla _eRevisor |
||
| 905 |
_aSoheir _eCataloger |
||
| 942 |
_2ddc _cTH |
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| 999 |
_c53806 _d53806 |
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