000 02710cam a2200349 a 4500
003 EG-GiCUC
005 20250223031351.0
008 151210s2015 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.27.M.Sc.2015.Sh.E
100 0 _aShimaa Mohamed Ahmed Abdelsalam
245 1 0 _aEvaluation of CD10 expression in urothelial bladder carcinoma :
_bHistopathological and immunohistochemical study /
_cShimaa Mohamed Ahmed Abdelsalam ; Supervised Ahmed Mahmoud Abdelaziz , Sahar Abdelhamed Tabak , Amira Mohammed Bassam
246 1 5 _aالتعبير عن ال"سى دى١٠" و علاقته بسرطان المثانه البوليه :
_bدراسة هستوباثولوجية و هستومناعية
260 _aCairo :
_bShimaa Mohamed Ahmed Abdelsalam ,
_c2015
300 _a121 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pathology
520 _aThe aim of this work is to study the immunohistochemical expression of CD10 in urothelial carcinoma of the urinary bladder and its possible prognostic value. Forty one radical cystectomy specimens; collected from the pathology department, Faculty of Medicine, Cairo University. Two slides were prepared from each paraffin embedded tumor block, one slide was stained for Hematoxylin and eosin (H and E) staining for histopathological reassessment and the other positively charged slide was stained immunohistochemically by CD10 monoclonal antibody. The immunohistochemical demonstration of the immunohistochemical marker was accomplished by using immunoperoxidase method. Staining of the cell membrane and/or cytoplasm was considered positive expression. A semi - quantitative scoring based on the percentage of positive cells was performed. Positive CD10 immunohistochemical expression was found to be significantly correlated with patients' age, tumor size, presence of squamoid differentiation and positive lymph node metastasis. Also there was significant correlation between CD10 scoring and presence of extravesical extension as well as vascular invasion. No significant correlation between CD10 immunohistochemical expression and tumor stage could be detected
530 _aIssued also as CD
653 4 _aCD10
653 4 _aUrinary bladder
653 4 _aUrothelial carcinoma
700 0 _aAhmed Mahmoud Abdelaziz ,
_eSupervisor
700 0 _aAmira Mohammed Bassam ,
_eSupervisor
700 0 _aSahar Abdelhamed Tabak ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSamia
_eCataloger
942 _2ddc
_cTH
999 _c53854
_d53854