000			02092cam a2200349 a 4500
003			EG-GiCUC
005			20250223031411.0
008			160117s2015 ua h f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aPh.D
099			_aCai01.08.03.Ph.D.2015.Lo.E
100	0		_aLobna Mohammed Abdelhalim
245	1	0	_aEnantioseparation and quantitative determination of some chiral switching drugs / _cLobna Mohammed Abdelhalim ; Supervised Laila Elsayed Abdelfattah , Maissa Yacoub Salem , Nahla Nour Eldin Ahmed Salama
246	1	5	_aالفصل الإنتقائى و التحليل الكمى لبعض الأدوية ذات خاصية التماثل المرأوى
260			_aCairo : _bLobna Mohammed Abdelhalim , _c2015
300			_a264 P. : _bfacsimiles ; _c25cm
502			_aThesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Analytical Chemistry
520			_aThe aim of this work is development and validation of new analytical techniques for enantioseparation and quantitative determination of some chiral switching drugs. In this thesis, zopiclone, ofloxacin, atracurium mesylate, ibuprofen, atropine sulphate, ketoprofen, and citalopram, were chosen to be studied as representative examples of chiral switching drugs to pure isomers, eszopiclone, levofloxacin, cisatracurium mesylate, dexibuprofen, hyoscyamine sulphate, dexketoprofen, escitalopram oxalate. The accuracy, selectivivity and applicability of the developed methods to the determination of enantiomeric purity and assay of chiral drugs in drug substances and drug products in QC laboratories were also studied
530			_aIssued also as CD
653		4	_aEnantiomer separation
653		4	_aOfloxacin
653		4	_aZopiclone
700	0		_aLaila Elsayed Abdelfattah , _eSupervisor
700	0		_aMaissa Yacoub Salem , _eSupervisor
700	0		_aNahla Nour Eldin Ahmed Salama , _eSupervisor
856			_uhttp://172.23.153.220/th.pdf
905			_aNazla _eRevisor
905			_aSamia _eCataloger
942			_2ddc _cTH
999			_c54537 _d54537