000 02800cam a2200349 a 4500
003 EG-GiCUC
005 20250223031414.0
008 160123s2015 ua h f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.11.31.Ph.D.2015.We.R
100 0 _aWesam Emam Aly Elmozy
245 1 4 _aThe role of delayed enhancement cardiac magnetic resonance imaging versus two dimensional echocardiography in the evaluation of hypertrophic cardiomyopathy disease in pediatrics /
_cWesam Emam Aly Elmozy ; Supervised Mervat Shafik Elsahragty , Saif Eldin Abaza Abdelmonem , Sonia Aly Alsaeidy
246 1 5 _aدور تصوير القلب بالرنين المغناطيسى بالتعزيز المتأخر للصبغة مقارنة بالموجات فوق الصوتية ثنائية الأبعاد فى تقييم مرض اعتلال عضلة القلب الضخامى فى الأطفال
260 _aCairo :
_bWesam Emam Aly Elmozy ,
_c2015
300 _a123 P. :
_bfacsimiles ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Radio-diagnosis
520 _aIn this study including ischemia, microvascular dysfunction, and obstruction. However, recent observations have challenged this interpretation showing that the stimulus for myocardial fibrosis is an early manifestation of sarcomere - gene mutations that may be present before occurrence of cardiac morphological features of HCM. Myocardial fibrosis is present in the majority of patients with overt HCM, and corresponds with impairment in myocardial energy metabolism, and correlates with the severity of ventricular dysfunction. Use of late Gd imaging has become a well - accepted technique to depict focal myocardial fibrosis correlating well with the autopsy findings. There is an increasing body of evidence that the presence and extent of myocardial fibrosis, in patients with HCM, is an independent predictor of adverse outcome, i.e., SCD, sustained ventricular tachycardia or fibrillation, and heart failure. Also in patients with no, or minimal symptoms, late Gd imaging adds prognostic value to conventional criteria for risk stratification. Moreover, myocardial fibrosis is related not only to an increased risk for SCD, but also to the presence of progressive disease and prediction of systolic and diastolic dysfunction
530 _aIssued also as CD
653 4 _aCMR
653 4 _aDCM
653 4 _aMRI
700 0 _aMervat Shafik Elsahragty ,
_eSupervisor
700 0 _aSaif Eldin Abaza Abdelmonem ,
_eSupervisor
700 0 _aSonia Aly Alsaeidy ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSamia
_eCataloger
942 _2ddc
_cTH
999 _c54652
_d54652