000			03337cam a2200349 a 4500
003			EG-GiCUC
005			20250223031436.0
008			160306s2015 ua dh f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aPh.D
099			_aCai01.11.31.Ph.D.2015.Sa.D
100	0		_aSafaa Ibrahim Saif Elnasr
245	1	4	_aThe diagnostic role of diffusion weighted imaging in addition to dynamic contrast MR mammography in assessment of breast cancer patients after surgical treatment / _cSafaa Ibrahim Saif El Nasr ; Supervised Soha Talaat Hamed , Maha Husein Helal , Rasha Wesam Abd elrahman
246	1	5	_aدورالرنين المغناطيسي بالانتشار الجزيئي بالاضافه الى الرنين المغناطيسى للثدى بالصبغة فى تقييم مرضى سرطان الثدى بعد العلاج الجراحى
260			_aCairo : _bSafaa Ibrahim Saif Elnasr , _c2015
300			_a120 P. : _bcharts , facsimiles ; _c25cm
502			_aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Radio-diagnosis
520			_aObjective: To assess the additive role of Diffusion weighted imaging (DWI) in addition to dynamic contrast-enhanced magnetic resonance mammography (DCE-MRM) in evaluating breast cancer patients who underwent surgery (conservative or radical) and radiotherapy.Patients and methods: 60 female patients were included in this prospective study. This study was conducted at both Kasr El-Ainy hospital, radiology department (Women{u2019}s imaging unit) and National Cancer Institute (N.C.I) from March-2013 until March 2015. All cases underwent either breast conservative therapy (BCT) or radical mastectomy at least 6 months before doing their MRI. Recurrence or post-operative complications were suspected by clinical examination. Mammography and breast US were done followed by MRI examination. DCM was done with DWI with b values of (0, 50, and 850). Pathology was the gold standard. Results: out of the 60 patients, 27 were pathologically proven as malignant lesions compared to 33 patients with variable spectrum of post operative changes. In our study, DCE- MRI was superior to DWI in diagnosis of malignant lesions with 2 false positive cases and no false negative cases while DWI showed 3 false negative cases and 4 false positive cases. DCE-MRI sequence & DWI showed sensitivity (100% ,88.9%), specificity (93.9% , 87.9%), PPV (93.1% , 88.9%), NPP (100% , 90.6%) & accuracy (96.7% , 88.3%) respectively .Conclusion: Although DWI is considered a promising diagnostic tool in the diagnosis of breast cancer, its interpretation requires awareness of its possible pitfalls, weakness and strengths. Better results are obtained by combing DWI with dynamic sequences. DWI possibly can be an alternative to contrast injection at certain conditions as in patients with renal impairment
530			_aIssued also as CD
653		4	_aBreast cancer
653		4	_aDiffusion Weighted Imaging
653		4	_aSurgical scarring
700	0		_aMaha Husein Helal , _eSupervisor
700	0		_aRasha Wesam Abdelrahman , _eSupervisor
700	0		_aSoha Talaat Hamed , _eSupervisor
856			_uhttp://172.23.153.220/th.pdf
905			_aEnas _eCataloger
905			_aNazla _eRevisor
942			_2ddc _cTH
999			_c55367 _d55367