000			02679cam a2200349 a 4500
003			EG-GiCUC
005			20250223031437.0
008			160307s2015 ua dh f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aM.Sc
099			_aCai01.11.27.M.Sc.2015.Pa.I
100	0		_aPassant Essam Eldin Ahmed
245	1	0	_aImmunohistochemical expression of fibronectin by stromal and epithelial cells in carcinoma of the female breast / _cPassant Essam Eldin Ahmed ; Supervised Fahima Mohamed Habib , Mohammed Faisal Darweesh , Lubna Omar Elfarouk Abdelsalam
246	1	5	_aالتعبير المناعى للفيبرونيكتين بواسطة الخلا يا اللحمية و الطلانية فى حالات سرطان الثدى فى الإناث
260			_aCairo : _bPassant Essam Eldin Ahmed , _c2015
300			_a192 P. : _bcharts , facsimiles ; _c25cm
502			_aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pathology
520			_aBreast cancer (BC) is the most common type of cancer among women world wide and leading cause of cancer related deaths. Distant metastases are responsible for the majority of cancer related deaths. Epithelial mesenchymal transition (EMT) is defined by the loss of epithelial characters and acquisition of mesenchymal phenotype. Through EMT, tumor cells acquire fibroblast like properties and exhibit increased motility, helping the escape of tumor cells from the primary tumors and metastasis. Fibronectin (FN) is an extracellular matrix glycoprotein constituting an important part of the tumor associated stroma. It is also considered a mesenchymal marker of EMT. Investigation of immunohistochemical expression of FN by epithelial and stromal cells of female BC and correlation of this expression with the clinico pathological aspects of the tumors. 50 formalin fixed paraffin embedded BC tissue sections were randomly collected. All the available data were collected from the patients{u2019} reports. The paraffin blocks were sectioned, stained with hematoxylin and eosin stains for histologic evaluation. Additional sections were immunostained with FN. Fibronectin expression was studied separately in the tumor cells and tumor stroma
530			_aIssued also as CD
653		4	_aBreast cancer
653		4	_aEMT
653		4	_aFibronectin
700	0		_aFahima Mohamed Habib , _eSupervisor
700	0		_aLubna Omar Elfarouk Abdelsalam , _eSupervisor
700	0		_aMohammed Faisal Darweesh , _eSupervisor
856			_uhttp://172.23.153.220/th.pdf
905			_aNazla _eRevisor
905			_aSamia _eCataloger
942			_2ddc _cTH
999			_c55394 _d55394