000 02733cam a2200349 a 4500
003 EG-GiCUC
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008 160309s2015 ua d f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.11.M.Sc.2015.Fi.R
100 0 _aFiras Lateef Kareem
245 1 4 _aThe role of vitamin D in PDE 5 inhibitors non responders /
_cFiras Lateef Kareem ; Supervised Taymour Mostafa , Dina Sabry , Ihab Abdellatif Osman
246 1 5 _aدور فيتامين د فى حالات القصور الجنسى الغير مستجاب لمثبطات الفوسفودايستريز
260 _aCairo :
_bFiras Lateef Kareem ,
_c2015
300 _a100 P. :
_bcharts ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Andrology and S.T.Ds
520 _aThis study aimed to assess serum vitamin D as well as vitamin D receptors (VDR) in men with erectile dysfunction (ED) non-responding to oral sildenafil citrate. The study included 160 men out of 684 presenting to the andrology, sexology and STIs department, Faculty of medicine, Cairo university after ethical approval and informed consent. In all, 160 men were allocated into; healthy potent men (n = 40), men with ED responders for sildenafil citrate (n = 60) and men with ED non responders for sildenafil citrate (n = 60). Inclusion criteria for sildenafil citrate non responders were an inadequate erectile response after at least 4 attempts using the highest tolerated drug dose in accordance with manufacturer{u2019}s guidelines with respect to timing relative to meals, use of concomitant medications and adequate sexual stimulation / arousal. Exclusion criteria were; diabetes mellitus, smoking, hypertension, dyslipidemia, cardiovascular disorders, hepatic or renal failures. They were subjected to; history taking, clinical examination, International Index of erectile function (IIEF) questionnaire, estimation of serum vitamin D and vitamin D receptor (VDR) gene expression. The results demonstrated that men with ED non responding for sildenafil demonstrated significant decrease in IIEF questionnaire scores, mean serum vitamin D as well as VDR expression compared with healthy potent men as well as men with ED responding to sildenafil
530 _aIssued also as CD
653 4 _aInhibitors non responders
653 4 _aPDE 5
653 4 _aVitamin D
700 0 _aDina Sabry ,
_eSupervisor
700 0 _aIhab Abdellatif Osman ,
_eSupervisor
700 0 _aTaymour Mostafa ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSamia
_eCataloger
942 _2ddc
_cTH
999 _c55453
_d55453