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003 EG-GiCUC
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008 160328s2015 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.27.M.Sc.2015.Ya.R
100 0 _aYasmin Yassin Ahmed
245 1 0 _aRole of cyclooxygenase 2 in invasive breast cancer (not otherwise specified) :
_bImmunohistochemical and pathological study /
_cYasmin Yassin Ahmed ; Supervised Maha Mosaad Mosaad , Hanan Hassan Mohamed Ali , Mohamad Faisal Darweesh
246 1 5 _a دور السيكلوأوكسيجيناس -2 فى سرطان الثدى :
_bدراسة مناعية وهستوكيميائية وهستوباثولوجية
260 _aCairo :
_bYasmin Yassin Ahmed ,
_c2015
300 _a122 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine- Department of Pathology
520 _aThe present study was performed on 40 selected cases of invasive ductal carcinoma; No special type (NST), selected randomly from Kasr Al Aini University Hospital. The aim of this study was to evaluate expression of cyclooxygenase -2 (COX-2) in invasive duct carcinoma of the breast (NST) and to correlate its expression with the available clinicopathological properties of cases of invasive duct carcinoma of the breast (NST) to assess the probability of using it as a prognostic marker. Expression of COX-2 using immunohistochemical staining was detected in 100% of the breast carcinoma samples. Lymph node status was highly significantly correlated with COX-2 overexpression, T stage in tumors were significantly correlated with COX-2 overexpression and there was inverse correlation between COX2 versus increasing age. No statistical significant correlation could be detected between COX-2 stain versus grade and tumor site. These results may suggest that COX-2 overexpression is associated with aggressive features and poor prognostic parameters in breast cancer
530 _aIssued also as CD
653 4 _aBreast cancer
653 4 _aCyclooxygenase-2
653 4 _aInvasive ductal carcinoma
700 0 _aHanan Hassan Mohamed Ali ,
_eSupervisor
700 0 _aMaha Mosaad Mosaad ,
_eSupervisor
700 0 _aMohamad Faisal Darweesh ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aAml
_eCataloger
905 _aNazla
_eRevisor
942 _2ddc
_cTH
999 _c55769
_d55769