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003 EG-GiCUC
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008 160823s2016 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.11.09.Ph.D.2016.Mo.S
100 0 _aMohamed Mahmoud Rashad Elbadawy Badr
245 1 0 _aStrong ion gap as a predictor of outcome in septic patients /
_cMohamed Mahmoud Rashad Elbadawy Badr ; Supervised Hassan Mohamed Khalid , Mahmoud Ali Elbadry , Abeer Mosbah Abdelhameed
246 1 5 _aفجوة الأيونات القوية كمؤشر للتنبؤ بنتاج مرضى التعفن الدموي
260 _aCairo :
_bMohamed Mahmoud Rashad Elbadawy Badr ,
_c2016
300 _a107 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Critical Care Medicine
520 _aBackground: Acid base disturbances, especially metabolic acidosis are common in septic patients. Physicochemical approach described by Stewart and modified by Figge quantify precisely metabolic acidosis and gives insight into its main mechanisms, as well as influence of unmeasured anion on metabolic acidosis. Aim. The aims of this study were to determine the role of acid base variables obtained on admission to ICU and 24 hours later predicting outcome in septic patients; whether the strong ion differences (SID) and strong ions gap (SIG) correlate with outcome from sepsis; comparison of predictive value of acid base variables or SID/SIG variables versus other well-known severity scores (like APATCHE II and SOFA scores). Results. Acute physiology and chronic health evaluation (APACHE II), SOFA score, SIG, SIDe, anion gap (AG), corrected anion gap and SBE were statistically significant predictors. Serum lactic acid had non-significant discriminating ability between survivors and non survivors, but lactate clearance had better ability. ROC analysis results showed that SIG followed by SIDe had the largest area below the curve and were more sensitive and specific than other predictors.
530 _aIssued also as CD
653 4 _aMetabolic acidosis
653 4 _aStrong ion difference
653 4 _aStrong ion gap
700 0 _aAbeer Mosbah Abdelhameed ,
_eSupervisor
700 0 _aHassan Mohamed Khalid ,
_eSupervisor
700 0 _aMahmoud Ali Elbadry ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSoheir
_eCataloger
942 _2ddc
_cTH
999 _c57521
_d57521