000			02099cam a2200349 a 4500
003			EG-GiCUC
005			20250223031546.0
008			160918s2016 ua dh f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aM.Sc
099			_aCai01.11.28.M.Sc.2016.Ra.S
100	0		_aRasha Hossam Eldin Mahfouz
245	1	0	_aStudy of serum syndecan-1 levels in juvenile systemic lupus erythematosus (JSLE) Egyptian patients / _cRasha Hossam Eldin Mahfouz ; Supervised Naglaa Abdelrahman Mosaad , Hala Mohamed Lotfy , Rasha Mohamad Hosny Shahin
246	1	5	_aدراسة نسبة السينديكان-1 في الأطفال المصريين المصابين بالذئبه الحمراء
260			_aCairo : _bRasha Hossam Eldin Mahfouz , _c2016
300			_a122 P. : _bcharts , facsimiles ; _c25cm
502			_aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics
520			_aSystemic Lupus Erythematosus (SLE) is characterized by loss of B-cell tolerance so Syndecan-1 (SDC-1) which is expressed on plasma cells derived from B-cells is thought to play a role in SLE . This is a cross-sectional study conducted on 60 JSLE patients and 30 healthy controls . Serum SDC-1 level was measured using ELISA technique and correlated with different clinical and laboratory data as well as SLEDAI-2K , renal SLEDAI , renal activity scores . Our results showed that Syndecan-1 is significantly higher in SLE patients compared with controls . Also, it has positive correlation with activity scores so it can be used as a marker for disease activity and renal activity in JSLE patients
530			_aIssued also as CD
653		4	_aJSLE
653		4	_aLupus nephritis
653		4	_aSLEDA{u2160}-2K score
700	0		_aHala Mohamed Lotfy , _eSupervisor
700	0		_aNaglaa Abdelrahman Mosaad , _eSupervisor
700	0		_aRasha Mohamad Hosny Shahin , _eSupervisor
856			_uhttp://172.23.153.220/th.pdf
905			_aNazla _eRevisor
905			_aSoheir _eCataloger
942			_2ddc _cTH
999			_c57739 _d57739