000 02955cam a2200349 a 4500
003 EG-GiCUC
005 20250223031559.0
008 170615s2016 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.28.M.Sc.2016.Ch.D
100 0 _aChristine Georges Salama Ayad
245 1 0 _aDetection of testicular adrenal rest tumour in boys with congenital adrenal hyperplasia using ultrasonography /
_cChristine Georges Salama Ayad ; Supervised Ghada Mohammad Anwar , Maha Mohsen Amin , Ahmed Mohammad Badr
246 1 5 _aالكشف عن اورام الخصية الناشئة من بقايا لخلايا الغدة الكظرية بما في الاطفال الذكور المصابين بتضخم الغدة الكظرية الخلقي باستخدام الموجات الصوتية
260 _aCairo :
_bChristine Georges Salama Ayad ,
_c2016
300 _a122 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics
520 _aTesticular adrenal rest tumour (TART) are a well known complication in adult male patients with CAH. With a reported prevalence up to 94%. In adulthood, the tumours are associated with gonadal dysfunction most probably due to longstanding obstruction of the seminiferous tubules. Because of paucity of studies done to detect TART in pediatric age group and because of importance of early diagnosis and treatment of TART in childhood for fertility protection of males with CAH, this study was applied to detect the presence of TART and its correlation with hormonal control and ther peutic regimen. It is a cross section study in which we studied 30 Egyptian male patients with CAH attended at DEMPU, with duration of the disease equal to or more than 3 years. All patients are on steroid therapy. The study included both patients with 21 hydroxylase deficiency and 11 beta hydroxylase deficiency; the salt wasting and simple virilizing form. The age range was (3.5 to 19 years old) with mean 8.72 years ± 4.48 SD. Our results showed that TART were present in 10% of cases at pediatric age group, it were detected at early childhood (at age 5 years) only after 3 years duration of the disease, it were detected in both SW and SV form of 21 OH deficiency type ofCAH, and it weren{u2019}t felt clinically in any of detected cases. We conclude that routine scrotal ultrasound in early childhood for early diagnosis and management of TART is very important
530 _aIssued also as CD
653 4 _aCAH
653 4 _aScrotal ultrasonography
653 4 _aTART
700 0 _aAhmed Mohammad Badr ,
_eSupervisor
700 0 _aGhada Mohammad Anwar ,
_eSupervisor
700 0 _aMaha Mohsen Amin ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aEnas
_eCataloger
905 _aNazla
_eRevisor
942 _2ddc
_cTH
999 _c58160
_d58160