000 02615cam a2200349 a 4500
003 EG-GiCUC
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008 161114s2016 ua o f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.07.10.M.Sc.2016.Om.S
100 0 _aOmnia Taha Hussein Mohamed
245 1 0 _aStudying virus resistance induction against bipartite begomovirus via gene silencing /
_cOmnia Taha Hussein Mohamed ; Supervised Naglaa Abdalmoneim Abdallah , Abdelhadi Abdallah Abdelhadi , Inas Farouk Fahmy
246 1 5 _aثنائيه الوحدات بواسطة الكبت الجينى لبعض جينات الفيروس Begomovirus دراسة على المقاومه الفيروسيه المستحدثه ضد
260 _aCairo :
_bOmnia Taha Hussein Mohamed ,
_c2016
300 _a104 P. :
_bphotographs ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Agriculture - Department of Genetics
520 _aSquash leaf curl virus (SqLCV) is a bipartite begomovirus affecting squash plants. In the last decade, SqlCV has been widely spread in the Middle East and caused huge yield loss in Egypt. It transmited by whitefly bemisia tabaci biotype B causing severe leaf curling, vein banding, molting ending by stunting as a late symptom. In this study posttranscriptional gene silencing (PTGS) has been induced to develop virus resistance. Two gene fragments from SqLCV were introduced in sense and antisense orientations using pFGC5941 vector to be expressed as a hairpin RNA (hpRNA). The first fragment was 348 bp at the 3' end of the replication associated protein gene (Rep or AC1), which had 50 bp overlapping with the transcription activation protein gene (TrAP or AC2). The second fragment was 879 bp representing the full sequence of the movement protein gene (BC1). Agrobacterium LB4404 was used in transient expression employing the syringe spotted technique in squash plants (cucurbita pepo L. cv. eskandarani). The infilterated plants harbouring the construct containing the Rep/TrAP fragment proved to be the best region for initiating PTGS
530 _aIssued also as CD
653 4 _aPost transcriptional gene silencing
653 4 _aSmall interfering RNA
653 4 _aSquash leaf curl virus
700 0 _aAbdelhadi Abdallah Abdelhadi ,
_eSupervisor
700 0 _aInas Farouk Fahmy ,
_eSupervisor
700 0 _aNaglaa Abdalmoneim Abdallah ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSamia
_eCataloger
942 _2ddc
_cTH
999 _c58612
_d58612