000			02754cam a2200349 a 4500
003			EG-GiCUC
005			20250223031648.0
008			170208s2016 ua dh f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aM.Sc
099			_aCai01.11.28.M.Sc.2016.As.R
100	0		_aAsmaa Salah eldin Ahmed Fathallah
245	1	0	_aRisk factors of ketoacidosis at the diagnosis of diabetes mellitus / _cAsmaa Salah eldin Ahmed Fathallah ; Supervised Mona Mamdouh Hassan , Amany Ibrahim Mohamed , Noha Arafa Mohamed
246	1	5	_aعوامل خطر الحماض الكيتونى عند تشخيص داء السكرى
260			_aCairo : _bAsmaa Salah eldin Ahmed Fathallah , _c2016
300			_a121 P. : _bcharts , facsimiles ; _c25cm
502			_aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics
520			_aIntroduction: Diabetes Mellitus (DM) is a metabolic disorder of glucose homeostasis and is one of the most common endocrine diseases in children worldwide. Diabetic ketoacidosis (DKA) is a common serious acute complication in children with DM. Its incidence in children at the onset of DM remains high, with approximately one-third presenting with mild DKA and one-sixth with moderate or severe DKA. Multiple factors affect the risk of developing DKA at the onset of DM in children. Aim of the study: to identify and analyze the risk factors associated with the development of ketoacidosis at the diagnosis of new cases with DM. Methods: Ninety nine children (53 DKA and 46 hyperglycemia) , age range from 1 month to 13 years, diagnosed with newly diagnosed diabetes, referred and managed at DEMPU in Children{u2019}s Hospital, Cairo University. Results: Classic symptoms (polyuria, polydipsia and weight loss) were the most common symptoms (93.8% & 92%) preceding the diagnosis; and diabetic ketoacidosis was present in 53.5%. Positive family history of diabetes was recorded in 54.5%, most of them with T2DM, but with no significant difference in the presentation. Delayed and missed diagnosis was recorded in 79.8% & 53.5% respectively, with significant difference affecting the presentation. Time lapse between diagnosis and start of insulin was found to be the most significant risk factor for developing DKA at diagnosis
530			_aIssued also as CD
653		4	_aDiabetes
653		4	_aDiabetic ketoacidosis
653		4	_aRisk factors
700	0		_aAmany Ibrahim Mohamed , _eSupervisor
700	0		_aMona Mamdouh Hassan , _eSupervisor
700	0		_aNoha Arafa Mohamed , _eSupervisor
856			_uhttp://172.23.153.220/th.pdf
905			_aNazla _eRevisor
905			_aShaima _eCataloger
942			_2ddc _cTH
999			_c59750 _d59750