000 03558cam a2200349 a 4500
003 EG-GiCUC
005 20250223031716.0
008 170412s2016 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.11.09.Ph.D.2016.Ib.S
100 0 _aIbrahim Mahmod Mohamed
245 1 0 _aSYNTAX score as a predictor of angiographic no-reflow in patients with ST segment elevation myocardial infarction treated with primary percutaneous coronary intervention /
_cIbrahim Mahmod Mohamed ; Supervised Hatem Elatroush , Dalia Ragab , Mohamed Fawzy
246 1 5 _aدراسة قدرة مقياس سينتاكس على التنبؤ بظاهرة عدم عودة سريان الدم بالشرايين التاجية بعد قسطرة القلب التداخلية الطارئة في مرضي الاحتشاء القلبي الحاد
260 _aCairo :
_bIbrahim Mahmod Mohamed ,
_c2016
300 _a228 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Critical Care Medicine
520 _aObjectives: The SYNTAX score (SXscore) has emerged as a reproducible angiographic tool to quantify the extent of coronary artery disease based on the location and complex-ity of each lesion. The aim of this study was to evaluate whether the SXscore is an independent predictor of no-reflow phenomenom and long-term cardiovascular outcomes in patients presented with acute ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (pPCI). Methods: A total of 760 patients with acute STEMI who were subjected to pPCI. Patients were categorized according to their TIMI flow grade into: normal flow (TIMI 3) 657 patients (86.4%) and noreflow (TIMI 0,1,2) 103 patients (13.6%) and according to Syntax scores into: mild (0-22){uF0E0} 292 patients who constituted 38.4% of the study group, moderate (23-32) {uF0E0} 338 patients who constituted 44.5% of the study group, severe (>32) {uF0E0} 130 patients who constituted 17.1% of the study group. Results: There were significant differences among the normal flow and noreflow groups with respect to age, basal glucose levels, and the incidences of diabetes mellitus, Killip class, onset of presentation, TIMI risk score and previous use of statins. There were increasing rates of culprit left anterior descending lesion (P < .001). No-reflow phenomenon was correlated to SYNTAX score, (r value .682, P value <.001).At longterm follow-up, all- cause mortality, non-fatal myocardial infarction, stroke, rehospitalization due to heart failure, and the need of revascularization were significantly more frequent among the patients in the noreflow group and highest SXscore. In multi-variate analysis, after including the SXscore as a numerical variable into the model, every point of increase was determined as an independent predictor for long-term mortality (hazard ratio [HR] 1.8, 95% confidence interval [CI] 1.139-2.95, P .013) and for overall major adverse cardiac events (MACEs; HR 1.44, 95% CI 1.33-1.56, P < .001)
530 _aIssued also as CD
653 4 _aAcute coronary syndromes
653 4 _aNoreflow
653 4 _aSYNTAX score
700 0 _aDalia Ragab ,
_eSupervisor
700 0 _aHatem Elatroush ,
_eSupervisor
700 0 _aMohamed Fawzy ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShaima
_eCataloger
942 _2ddc
_cTH
999 _c60659
_d60659